Rhabdomyolysis after the use of tranexamic acid in a patient with hereditary angioedema

Authors

  • Emilie Karan Maia Centro Universitário de Brasília - UniCEUB
  • Fernanda Casares Marcelino Secretaria de Estado de Saúde do Distrito Federal - SES-DF
  • Fernanda Suelen Jacques Sousa de Assis Hospital Universitário de Brasília - HUB
  • Carmen Déa Ribeiro de Paula Hospital Universitário de Brasília - HUB

DOI:

https://doi.org/10.51723/ccs.v30i03.456

Keywords:

Hereditary angioedema, Tranexamic acid, Rhabdomyolysis

Abstract

The hereditary angioedema, a genetic disorder with exacerbated bradykinin production and generalized edema, has different symptoms that arise without any causal factor. Treatment consists of the use of rescue medications during crises and short- and long-term prophylaxis. Objective: to report the case of a patient treated with tranexamic acid, an antifibrinolytic agent, who had elevated urea, creatinine and creatine phosphokinase, receiving the diagnosis of acute kidney injury by rhabdomyolysis. After discontinuing the drug, kidney function improved and the enzyme decreased. Conclusion: rhabdomyolysis is an effect described with the use of epsilon-aminocaproic acid, but not with tranexamic acid.

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Author Biographies

  • Emilie Karan Maia, Centro Universitário de Brasília - UniCEUB

    Estudante de Graduação do Curso de Medicina

  • Fernanda Casares Marcelino, Secretaria de Estado de Saúde do Distrito Federal - SES-DF

    Médica Alergologista do Hospital Regional da Asa Norte - HRAN - SES-DF 

  • Fernanda Suelen Jacques Sousa de Assis, Hospital Universitário de Brasília - HUB

    Médica Residente de Dermatologia do HUB

  • Carmen Déa Ribeiro de Paula, Hospital Universitário de Brasília - HUB

    Médica Dermatologista do HUB

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Published

2020-12-08

Issue

Section

Clínica Assistencial

How to Cite

1.
Rhabdomyolysis after the use of tranexamic acid in a patient with hereditary angioedema. Com. Ciências Saúde [Internet]. 2020 Dec. 8 [cited 2024 Nov. 20];30(03):41-5. Available from: https://revistaccs.espdf.fepecs.edu.br/index.php/comunicacaoemcienciasdasaude/article/view/456

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