Novas tecnologias para estudo da tuberculose: Uma análise da detecção e transmissão de M. tuberculosis circulante

Autores/as

  • Maria Lucia Rosa Rossetti Universidade Luterana do Brasil
  • Elis Regina Dalla-Costa Centro de Desenvolvimento Científico e Tecnológico (CDCT), Secretaria Estadual da Saúde (SES/RS), Porto Alegre, Rio Grande do Sul
  • Marcia Susana Nunes Silva Universidade Luterana do Brasil
  • Natali Linck Secretaria Estadual da Saúde - SES/RS
  • Pedro Eduardo Almeida da Silva Fundação Universidade do Rio Grande (FURG), Rio Grande, Rio Grande do Sul.

DOI:

https://doi.org/10.51723/ccs.v28i01.124

Palabras clave:

tuberculose, epidemiologia molecular, diagnóstico por PCR, resistência

Resumen

Além de identificar os doentes com tuberculose (TB), é importante monitorar os genótipos de M. tuberculosis circulantes. Mesmo após a implantação do Xpert® MTB/RIF, o diagnóstico é ainda realizado apenas pela baciloscopia, que apresenta baixa sensibilidade, na maioria dos laboratórios. Objetivo: Utilizar análises de DNA para o diagnóstico e identificação dos genótipos circulantes em uma população do Rio Grande do Sul, Brasil. Metodologia: Amostras clínicas foram analisadas pelo Detect-TB (Labtest, MG), por PCR em tempo real (Xpert® MTB/RIF) e comparados a baciloscopia. A genotipagem foi realizada por spoligotyping.
Resultados: A acurácia do Detect-TB para a identificação da TB foi similar ao Xpert® MTB/RIF, sendo que o Detect-TB foi mais custo-efetivo quando utilizado em conjunto com a baciloscopia. Os genótipos LAM5, RDRio e like-Pinni2, relacionados a resistência ao tratamento, estavam sendo transmitidos neste grupo, e a maioria dos resistentes a isoniazida (78,5%) e dos resistentes a rifampicina (92,1%) apresentavam as mutações mais conhecidas. Conclusão: A aplicação de tecnologias de DNA pode auxiliar no controle de TB, tanto no diagnóstico rápido quanto na identificação de perfis resistentes, viabilizando tratamento adequado aos pacientes.

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Biografía del autor/a

  • Maria Lucia Rosa Rossetti, Universidade Luterana do Brasil

    - Curso de pós-graduação em biologia molecular e celular aplicado a Saúde, Universidade Luterana do Brasil (ULBRA), Canoas, Rio Grande do Sul.
    - Centro de Desenvolvimento Científico e Tecnológico (CDCT), Secretaria Estadual da Saúde (SES/RS), Porto Alegre, Rio Grande do Sul

    Correspondência:
    Maria Lucia Rosa Rossetti
    Endereço: Rua carvalho Monteiro, 210/201 Petrópolis 90470-100
    Endereço eletrônico: mrossett@terra.com.br
    Telefone de contato: 51 34774000/2474 e 984054239

  • Marcia Susana Nunes Silva, Universidade Luterana do Brasil

    Curso de pós-graduação em biologia molecular e celular aplicado a Saúde,
    Universidade Luterana do Brasil (ULBRA), Canoas, Rio Grande do Sul

  • Natali Linck, Secretaria Estadual da Saúde - SES/RS

    Centro de Desenvolvimento Científico e Tecnológico (CDCT), Secretaria Estadual da Saúde (SES/RS), Porto Alegre, Rio Grande do Sul.

Referencias

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Publicado

2018-02-09

Número

Vol. 28 Núm. 01 (2017): CCS

Sección

Clínica Assistencial

Licencia

Declaro para os devidos fins que o artigo que estou submetendo representa um trabalho original e nunca foi publicado total ou parcialmente, e que se alguma de suas partes foi publicada possuímos autorização expressa para a publicação no periódico Comunicação em Ciências da Saúde (CCS). Esse artigo não foi enviado a outro periódico e não o será enquanto estiver sendo considerada sua publicação; caso venha a ser aceito não será publicado em outro periódico; e não contém material difamatório ou ilegal sob nenhuma forma, não viola a intimidade de terceiros, nem infringe direitos protegidos.

Eu e demais autores desse trabalho certificamos por meio desta declaração que:

  • Concordamos com as normas editoriais e com o processo de revisão da CCS;
  • Aceitamos a responsabilidade pela conduta desse estudo e pela análise e interpretação dos dados;
  • Cooperaremos, sempre que solicitado, na obtenção e fornecimento de dados sobre os quais o manuscrito está baseado, para exame dos avaliadores;
  • Não estão sendo omitidos quaisquer ligações ou acordos de financiamento entre os autores e companhias ou pessoas que possam ter interesse no material abordado no artigo;
  • Não estão sendo excluídos ou omitidos deste artigo autores ou instituições participantes;
  • Possuímos permissão para uso de figuras e tabelas publicadas em outras fontes;
  • Possuímos permissão das pessoas e instituições citadas nos agradecimentos;
  • O autor correspondente autoriza a publicação do endereço informado e e-mail do(s) autor(es) junto com o artigo;
  • Assumimos a responsabilidade pela entrega de documentos verídicos;
  • Autorizamos a publicação do referido artigo no periódico Comunicação em Ciências da Saúde, segundo critérios próprios e em número e volume a serem definidos pelo editor do periódico;
  • Nos comprometemos a atender os prazos estipulados pelos editores do periódico Comunicação em Ciências da saúde;
  • Estamos cientes de que a não manifestação no prazo de dois dias da revisão da diagramação, recebida por e-mail, será considerado aprovado para publicação.

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public $registered_filters = [...]; public $registered_resources = [...]; public $registered_cache_resources = [...]; public $autoload_filters = [...]; public $default_modifiers = [...]; public $escape_html = FALSE; public $start_time = 1732446780.1848; public $_current_file = NULL; public $_parserdebug = FALSE; public $_debug = NULL; protected $template_dir = [...]; protected $_processedTemplateDir = [...]; protected $config_dir = '/var/www/html/cache/t_config'; protected $_processedConfigDir = [...]; protected $compile_dir = '/var/www/html/cache/t_compile/'; protected $plugins_dir = [...]; protected $cache_dir = '/var/www/html/cache/t_cache'; protected $obsoleteProperties = [...]; protected $accessMap = [...]; private ${Smarty}isMutingUndefinedOrNullWarnings = FALSE; private ${PKP\template\PKPTemplateManager}_styleSheets = [...]; private ${PKP\template\PKPTemplateManager}_javaScripts = [...]; private ${PKP\template\PKPTemplateManager}_htmlHeaders = [...]; private ${PKP\template\PKPTemplateManager}_constants = [...]; private ${PKP\template\PKPTemplateManager}_localeKeys = [...]; protected $_state = [...]; private ${PKP\template\PKPTemplateManager}_cacheability = 'no-store'; private ${PKP\template\PKPTemplateManager}_fbv = class PKP\form\FormBuilderVocabulary { ... }; private ${PKP\template\PKPTemplateManager}_request = class APP\core\Request { ... }; private array ${PKP\template\PKPTemplateManager}headers = [...]; private bool ${PKP\template\PKPTemplateManager}isBackendPage = FALSE }; public $config_vars = []; public $ext = class Smarty_Internal_Extension_Handler { public $objType = 2; private $_property_info = [...]; private $resolvedProperties = [...]; public $getTemplateVars = class Smarty_Internal_Method_GetTemplateVars { ... } }; public $cache_id = NULL; public $compile_id = '42362804174f266c598cdb32c3208fc745b92101'; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = []; public $_cache = []; public $smarty = class APP\template\TemplateManager { public $_objType = 1; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = [...]; public $parent = NULL; public $config_vars = [...]; public $ext = class Smarty_Internal_Extension_Handler { ... }; public $cache_id = NULL; public $compile_id = NULL; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = [...]; public $_cache = [...]; public $auto_literal = TRUE; public $error_unassigned = FALSE; public $use_include_path = FALSE; public $_templateDirNormalized = TRUE; public $_joined_template_dir = '/var/www/html/templates/#/var/www/html/plugins/themes/default/templates/'; public $_configDirNormalized = FALSE; public $_joined_config_dir = NULL; public $default_template_handler_func = NULL; public $default_config_handler_func = NULL; public $default_plugin_handler_func = NULL; public $_compileDirNormalized = TRUE; public $_pluginsDirNormalized = FALSE; public $_cacheDirNormalized = FALSE; public $force_compile = FALSE; public $use_sub_dirs = FALSE; public $allow_ambiguous_resources = FALSE; public $merge_compiled_includes = FALSE; public $extends_recursion = TRUE; public $force_cache = FALSE; public $left_delimiter = '{'; public $right_delimiter = '}'; public $literals = [...]; public $security_class = 'Smarty_Security'; public $security_policy = NULL; public $allow_php_templates = FALSE; public $debugging = FALSE; public $debugging_ctrl = 'NONE'; public $smarty_debug_id = 'SMARTY_DEBUG'; public $debug_tpl = NULL; public $error_reporting = 32757; public $config_overwrite = TRUE; public $config_booleanize = TRUE; public $config_read_hidden = FALSE; public $compile_locking = TRUE; public $cache_locking = FALSE; public $locking_timeout = 10; public $default_resource_type = 'app'; public $caching_type = 'file'; public $default_config_type = 'file'; public $cache_modified_check = FALSE; public $registered_plugins = [...]; public $registered_objects = [...]; public $registered_classes = [...]; public $registered_filters = [...]; public $registered_resources = [...]; public $registered_cache_resources = [...]; public $autoload_filters = [...]; public $default_modifiers = [...]; public $escape_html = FALSE; public $start_time = 1732446780.1848; public $_current_file = NULL; public $_parserdebug = FALSE; public $_debug = NULL; protected $template_dir = [...]; protected $_processedTemplateDir = [...]; protected $config_dir = '/var/www/html/cache/t_config'; protected $_processedConfigDir = [...]; protected $compile_dir = '/var/www/html/cache/t_compile/'; protected $plugins_dir = [...]; protected $cache_dir = '/var/www/html/cache/t_cache'; protected $obsoleteProperties = [...]; protected $accessMap = [...]; private ${Smarty}isMutingUndefinedOrNullWarnings = FALSE; private ${PKP\template\PKPTemplateManager}_styleSheets = [...]; private ${PKP\template\PKPTemplateManager}_javaScripts = [...]; private ${PKP\template\PKPTemplateManager}_htmlHeaders = [...]; private ${PKP\template\PKPTemplateManager}_constants = [...]; private ${PKP\template\PKPTemplateManager}_localeKeys = [...]; protected $_state = [...]; private ${PKP\template\PKPTemplateManager}_cacheability = 'no-store'; private ${PKP\template\PKPTemplateManager}_fbv = class PKP\form\FormBuilderVocabulary { ... }; private ${PKP\template\PKPTemplateManager}_request = class APP\core\Request { ... }; private array ${PKP\template\PKPTemplateManager}headers = [...]; private bool ${PKP\template\PKPTemplateManager}isBackendPage = FALSE }; public $source = class Smarty_Template_Source { public $uid = '1c372c95cd85572e0fbc9a53d0323a0b229cfc78'; public $resource = 'frontend/pages/article.tpl'; public $type = 'app'; public $name = 'frontend/pages/article.tpl'; public $filepath = 'app:frontendpagesarticle.tpl'; public $timestamp = 1724439197; public $exists = TRUE; public $basename = NULL; public $components = NULL; public $handler = class PKP\template\PKPTemplateResource { ... }; public $smarty = class APP\template\TemplateManager { ... }; public $isConfig = FALSE; public $content = NULL; public $compiler_class = 'Smarty_Internal_SmartyTemplateCompiler'; public $template_lexer_class = 'Smarty_Internal_Templatelexer'; public $template_parser_class = 'Smarty_Internal_Templateparser' }; public $inheritance = NULL; public $template_resource = 'frontend/pages/article.tpl'; public $mustCompile = FALSE; public $templateId = '/var/www/html/templates/#/var/www/html/plugins/themes/default/templates/#app:frontend/pages/article.tpl##42362804174f266c598cdb32c3208fc745b92101#0'; public $scope = 0; public $isRenderingCache = FALSE; public $startRenderCallbacks = []; public $endRenderCallbacks = []; public $compiled = class Smarty_Template_Compiled { public $filepath = '/var/www/html/cache/t_compile/42362804174f266c598cdb32c3208fc745b92101^1c372c95cd85572e0fbc9a53d0323a0b229cfc78_0.app.frontendpagesarticle.tpl.php'; public $timestamp = 1732299637; public $exists = TRUE; public $compile_id = NULL; public $processed = TRUE; public $unifunc = 'content_6740cb7558aae9_79447201'; public $has_nocache_code = FALSE; public $file_dependency = [...]; public $content = NULL; public $includes = [...]; public $isCache = FALSE; public $nocache_hash = NULL } } ).../smarty_internal_template.php:217
130.165623380904Smarty_Template_Resource_Base->getRenderedTemplateCode( $_template = class Smarty_Internal_Template { public $_objType = 2; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = ['SCRIPT_NAME' => class Smarty_Variable { ... }, 'defaultCharset' => class Smarty_Variable { ... }, 'baseUrl' => class Smarty_Variable { ... }, 'currentContext' => class Smarty_Variable { ... }, 'currentLocale' => class Smarty_Variable { ... }, 'currentLocaleLangDir' => class Smarty_Variable { ... }, 'applicationName' => class Smarty_Variable { ... }, 'dateFormatShort' => class Smarty_Variable { ... }, 'dateFormatLong' => class Smarty_Variable { ... }, 'datetimeFormatShort' => class Smarty_Variable { ... }, 'datetimeFormatLong' => class Smarty_Variable { ... }, 'timeFormat' => class Smarty_Variable { ... }, 'displayPageHeaderTitle' => class Smarty_Variable { ... }, 'displayPageHeaderLogo' => class Smarty_Variable { ... }, 'displayPageHeaderLogoAltText' => class Smarty_Variable { ... }, 'activeTheme' => class Smarty_Variable { ... }, 'requestedPage' => class Smarty_Variable { ... }, 'requestedOp' => class Smarty_Variable { ... }, 'fbvStyles' => class Smarty_Variable { ... }, 'isUserLoggedIn' => class Smarty_Variable { ... }, 'isUserLoggedInAs' => class Smarty_Variable { ... }, 'itemsPerPage' => class Smarty_Variable { ... }, 'numPageLinks' => class Smarty_Variable { ... }, 'siteTitle' => class Smarty_Variable { ... }, 'hasSidebar' => class Smarty_Variable { ... }, 'brandImage' => class Smarty_Variable { ... }, 'sitePublicFilesDir' => class Smarty_Variable { ... }, 'publicFilesDir' => class Smarty_Variable { ... }, 'currentJournal' => class Smarty_Variable { ... }, 'primaryLocale' => class Smarty_Variable { ... }, 'supportedLocales' => class Smarty_Variable { ... }, 'enableAnnouncements' => class Smarty_Variable { ... }, 'disableUserReg' => class Smarty_Variable { ... }, 'pageFooter' => class Smarty_Variable { ... }, 'issue' => class Smarty_Variable { ... }, 'article' => class Smarty_Variable { ... }, 'publication' => class Smarty_Variable { ... }, 'currentPublication' => class Smarty_Variable { ... }, 'galley' => class Smarty_Variable { ... }, 'fileId' => class Smarty_Variable { ... }, 'submissionFileId' => class Smarty_Variable { ... }, 'userRoles' => class Smarty_Variable { ... }, 'firstPublication' => class Smarty_Variable { ... }, 'ccLicenseBadge' => class Smarty_Variable { ... }, 'section' => class Smarty_Variable { ... }, 'categories' => class Smarty_Variable { ... }, 'primaryGalleys' => class Smarty_Variable { ... }, 'supplementaryGalleys' => class Smarty_Variable { ... }, 'userGroupsById' => class Smarty_Variable { ... }, 'parsedCitations' => class Smarty_Variable { ... }, 'licenseTerms' => class Smarty_Variable { ... }, 'licenseUrl' => class Smarty_Variable { ... }, 'copyrightHolder' => class Smarty_Variable { ... }, 'copyrightYear' => class Smarty_Variable { ... }, 'pubIdPlugins' => class Smarty_Variable { ... }, 'keywords' => class Smarty_Variable { ... }, 'hasAccess' => class Smarty_Variable { ... }, 'citation' => class Smarty_Variable { ... }, 'citationArgs' => class Smarty_Variable { ... }, 'citationArgsJson' => class Smarty_Variable { ... }, 'citationStyles' => class Smarty_Variable { ... }, 'citationDownloads' => class Smarty_Variable { ... }, 'state' => class Smarty_Variable { ... }]; public $parent = class APP\template\TemplateManager { public $_objType = 1; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = [...]; public $parent = NULL; public $config_vars = [...]; public $ext = class Smarty_Internal_Extension_Handler { ... }; public $cache_id = NULL; public $compile_id = NULL; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = [...]; public $_cache = [...]; public $auto_literal = TRUE; public $error_unassigned = FALSE; public $use_include_path = FALSE; public $_templateDirNormalized = TRUE; public $_joined_template_dir = '/var/www/html/templates/#/var/www/html/plugins/themes/default/templates/'; public $_configDirNormalized = FALSE; public $_joined_config_dir = NULL; public $default_template_handler_func = NULL; public $default_config_handler_func = NULL; public $default_plugin_handler_func = NULL; public $_compileDirNormalized = TRUE; public $_pluginsDirNormalized = FALSE; public $_cacheDirNormalized = FALSE; public $force_compile = FALSE; public $use_sub_dirs = FALSE; public $allow_ambiguous_resources = FALSE; public $merge_compiled_includes = FALSE; public $extends_recursion = TRUE; public $force_cache = FALSE; public $left_delimiter = '{'; public $right_delimiter = '}'; public $literals = [...]; public $security_class = 'Smarty_Security'; public $security_policy = NULL; public $allow_php_templates = FALSE; public $debugging = FALSE; public $debugging_ctrl = 'NONE'; public $smarty_debug_id = 'SMARTY_DEBUG'; public $debug_tpl = NULL; public $error_reporting = 32757; public $config_overwrite = TRUE; public $config_booleanize = TRUE; public $config_read_hidden = FALSE; public $compile_locking = TRUE; public $cache_locking = FALSE; public $locking_timeout = 10; public $default_resource_type = 'app'; public $caching_type = 'file'; public $default_config_type = 'file'; public $cache_modified_check = FALSE; public $registered_plugins = [...]; public $registered_objects = [...]; public $registered_classes = [...]; public $registered_filters = [...]; public $registered_resources = [...]; public $registered_cache_resources = [...]; public $autoload_filters = [...]; public $default_modifiers = [...]; public $escape_html = FALSE; public $start_time = 1732446780.1848; public $_current_file = NULL; public $_parserdebug = FALSE; public $_debug = NULL; protected $template_dir = [...]; protected $_processedTemplateDir = [...]; protected $config_dir = '/var/www/html/cache/t_config'; protected $_processedConfigDir = [...]; protected $compile_dir = '/var/www/html/cache/t_compile/'; protected $plugins_dir = [...]; protected $cache_dir = '/var/www/html/cache/t_cache'; protected $obsoleteProperties = [...]; protected $accessMap = [...]; private ${Smarty}isMutingUndefinedOrNullWarnings = FALSE; private ${PKP\template\PKPTemplateManager}_styleSheets = [...]; private ${PKP\template\PKPTemplateManager}_javaScripts = [...]; private ${PKP\template\PKPTemplateManager}_htmlHeaders = [...]; private ${PKP\template\PKPTemplateManager}_constants = [...]; private ${PKP\template\PKPTemplateManager}_localeKeys = [...]; protected $_state = [...]; private ${PKP\template\PKPTemplateManager}_cacheability = 'no-store'; private ${PKP\template\PKPTemplateManager}_fbv = class PKP\form\FormBuilderVocabulary { ... }; private ${PKP\template\PKPTemplateManager}_request = class APP\core\Request { ... }; private array ${PKP\template\PKPTemplateManager}headers = [...]; private bool ${PKP\template\PKPTemplateManager}isBackendPage = FALSE }; public $config_vars = []; public $ext = class Smarty_Internal_Extension_Handler { public $objType = 2; private $_property_info = [...]; private $resolvedProperties = [...]; public $getTemplateVars = class Smarty_Internal_Method_GetTemplateVars { ... } }; public $cache_id = NULL; public $compile_id = '42362804174f266c598cdb32c3208fc745b92101'; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = []; public $_cache = []; public $smarty = class APP\template\TemplateManager { public $_objType = 1; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = [...]; public $parent = NULL; public $config_vars = [...]; public $ext = class Smarty_Internal_Extension_Handler { ... }; public $cache_id = NULL; public $compile_id = NULL; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = [...]; public $_cache = [...]; public $auto_literal = TRUE; public $error_unassigned = FALSE; public $use_include_path = FALSE; public $_templateDirNormalized = TRUE; public $_joined_template_dir = '/var/www/html/templates/#/var/www/html/plugins/themes/default/templates/'; public $_configDirNormalized = FALSE; public $_joined_config_dir = NULL; public $default_template_handler_func = NULL; public $default_config_handler_func = NULL; public $default_plugin_handler_func = NULL; public $_compileDirNormalized = TRUE; public $_pluginsDirNormalized = FALSE; public $_cacheDirNormalized = FALSE; public $force_compile = FALSE; public $use_sub_dirs = FALSE; public $allow_ambiguous_resources = FALSE; public $merge_compiled_includes = FALSE; public $extends_recursion = TRUE; public $force_cache = FALSE; public $left_delimiter = '{'; public $right_delimiter = '}'; public $literals = [...]; public $security_class = 'Smarty_Security'; public $security_policy = NULL; public $allow_php_templates = FALSE; public $debugging = FALSE; public $debugging_ctrl = 'NONE'; public $smarty_debug_id = 'SMARTY_DEBUG'; public $debug_tpl = NULL; public $error_reporting = 32757; public $config_overwrite = TRUE; public $config_booleanize = TRUE; public $config_read_hidden = FALSE; public $compile_locking = TRUE; public $cache_locking = FALSE; public $locking_timeout = 10; public $default_resource_type = 'app'; public $caching_type = 'file'; public $default_config_type = 'file'; public $cache_modified_check = FALSE; public $registered_plugins = [...]; public $registered_objects = [...]; public $registered_classes = [...]; public $registered_filters = [...]; public $registered_resources = [...]; public $registered_cache_resources = [...]; public $autoload_filters = [...]; public $default_modifiers = [...]; public $escape_html = FALSE; public $start_time = 1732446780.1848; public $_current_file = NULL; public $_parserdebug = FALSE; public $_debug = NULL; protected $template_dir = [...]; protected $_processedTemplateDir = [...]; protected $config_dir = '/var/www/html/cache/t_config'; protected $_processedConfigDir = [...]; protected $compile_dir = '/var/www/html/cache/t_compile/'; protected $plugins_dir = [...]; protected $cache_dir = '/var/www/html/cache/t_cache'; protected $obsoleteProperties = [...]; protected $accessMap = [...]; private ${Smarty}isMutingUndefinedOrNullWarnings = FALSE; private ${PKP\template\PKPTemplateManager}_styleSheets = [...]; private ${PKP\template\PKPTemplateManager}_javaScripts = [...]; private ${PKP\template\PKPTemplateManager}_htmlHeaders = [...]; private ${PKP\template\PKPTemplateManager}_constants = [...]; private ${PKP\template\PKPTemplateManager}_localeKeys = [...]; protected $_state = [...]; private ${PKP\template\PKPTemplateManager}_cacheability = 'no-store'; private ${PKP\template\PKPTemplateManager}_fbv = class PKP\form\FormBuilderVocabulary { ... }; private ${PKP\template\PKPTemplateManager}_request = class APP\core\Request { ... }; private array ${PKP\template\PKPTemplateManager}headers = [...]; private bool ${PKP\template\PKPTemplateManager}isBackendPage = FALSE }; public $source = class Smarty_Template_Source { public $uid = '1c372c95cd85572e0fbc9a53d0323a0b229cfc78'; public $resource = 'frontend/pages/article.tpl'; public $type = 'app'; public $name = 'frontend/pages/article.tpl'; public $filepath = 'app:frontendpagesarticle.tpl'; public $timestamp = 1724439197; public $exists = TRUE; public $basename = NULL; public $components = NULL; public $handler = class PKP\template\PKPTemplateResource { ... }; public $smarty = class APP\template\TemplateManager { ... }; public $isConfig = FALSE; public $content = NULL; public $compiler_class = 'Smarty_Internal_SmartyTemplateCompiler'; public $template_lexer_class = 'Smarty_Internal_Templatelexer'; public $template_parser_class = 'Smarty_Internal_Templateparser' }; public $inheritance = NULL; public $template_resource = 'frontend/pages/article.tpl'; public $mustCompile = FALSE; public $templateId = '/var/www/html/templates/#/var/www/html/plugins/themes/default/templates/#app:frontend/pages/article.tpl##42362804174f266c598cdb32c3208fc745b92101#0'; public $scope = 0; public $isRenderingCache = FALSE; public $startRenderCallbacks = []; public $endRenderCallbacks = []; public $compiled = class Smarty_Template_Compiled { public $filepath = '/var/www/html/cache/t_compile/42362804174f266c598cdb32c3208fc745b92101^1c372c95cd85572e0fbc9a53d0323a0b229cfc78_0.app.frontendpagesarticle.tpl.php'; public $timestamp = 1732299637; public $exists = TRUE; public $compile_id = NULL; public $processed = TRUE; public $unifunc = 'content_6740cb7558aae9_79447201'; public $has_nocache_code = FALSE; public $file_dependency = [...]; public $content = NULL; public $includes = [...]; public $isCache = FALSE; public $nocache_hash = NULL } }, $unifunc = ??? ).../smarty_template_compiled.php:114
140.165623380904content_6740cb7558aae9_79447201( $_smarty_tpl = class Smarty_Internal_Template { public $_objType = 2; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = ['SCRIPT_NAME' => class Smarty_Variable { ... }, 'defaultCharset' => class Smarty_Variable { ... }, 'baseUrl' => class Smarty_Variable { ... }, 'currentContext' => class Smarty_Variable { ... }, 'currentLocale' => class Smarty_Variable { ... }, 'currentLocaleLangDir' => class Smarty_Variable { ... }, 'applicationName' => class Smarty_Variable { ... }, 'dateFormatShort' => class Smarty_Variable { ... }, 'dateFormatLong' => class Smarty_Variable { ... }, 'datetimeFormatShort' => class Smarty_Variable { ... }, 'datetimeFormatLong' => class Smarty_Variable { ... }, 'timeFormat' => class Smarty_Variable { ... }, 'displayPageHeaderTitle' => class Smarty_Variable { ... }, 'displayPageHeaderLogo' => class Smarty_Variable { ... }, 'displayPageHeaderLogoAltText' => class Smarty_Variable { ... }, 'activeTheme' => class Smarty_Variable { ... }, 'requestedPage' => class Smarty_Variable { ... }, 'requestedOp' => class Smarty_Variable { ... }, 'fbvStyles' => class Smarty_Variable { ... }, 'isUserLoggedIn' => class Smarty_Variable { ... }, 'isUserLoggedInAs' => class Smarty_Variable { ... }, 'itemsPerPage' => class Smarty_Variable { ... }, 'numPageLinks' => class Smarty_Variable { ... }, 'siteTitle' => class Smarty_Variable { ... }, 'hasSidebar' => class Smarty_Variable { ... }, 'brandImage' => class Smarty_Variable { ... }, 'sitePublicFilesDir' => class Smarty_Variable { ... }, 'publicFilesDir' => class Smarty_Variable { ... }, 'currentJournal' => class Smarty_Variable { ... }, 'primaryLocale' => class Smarty_Variable { ... }, 'supportedLocales' => class Smarty_Variable { ... }, 'enableAnnouncements' => class Smarty_Variable { ... }, 'disableUserReg' => class Smarty_Variable { ... }, 'pageFooter' => class Smarty_Variable { ... }, 'issue' => class Smarty_Variable { ... }, 'article' => class Smarty_Variable { ... }, 'publication' => class Smarty_Variable { ... }, 'currentPublication' => class Smarty_Variable { ... }, 'galley' => class Smarty_Variable { ... }, 'fileId' => class Smarty_Variable { ... }, 'submissionFileId' => class Smarty_Variable { ... }, 'userRoles' => class Smarty_Variable { ... }, 'firstPublication' => class Smarty_Variable { ... }, 'ccLicenseBadge' => class Smarty_Variable { ... }, 'section' => class Smarty_Variable { ... }, 'categories' => class Smarty_Variable { ... }, 'primaryGalleys' => class Smarty_Variable { ... }, 'supplementaryGalleys' => class Smarty_Variable { ... }, 'userGroupsById' => class Smarty_Variable { ... }, 'parsedCitations' => class Smarty_Variable { ... }, 'licenseTerms' => class Smarty_Variable { ... }, 'licenseUrl' => class Smarty_Variable { ... }, 'copyrightHolder' => class Smarty_Variable { ... }, 'copyrightYear' => class Smarty_Variable { ... }, 'pubIdPlugins' => class Smarty_Variable { ... }, 'keywords' => class Smarty_Variable { ... }, 'hasAccess' => class Smarty_Variable { ... }, 'citation' => class Smarty_Variable { ... }, 'citationArgs' => class Smarty_Variable { ... }, 'citationArgsJson' => class Smarty_Variable { ... }, 'citationStyles' => class Smarty_Variable { ... }, 'citationDownloads' => class Smarty_Variable { ... }, 'state' => class Smarty_Variable { ... }]; public $parent = class APP\template\TemplateManager { public $_objType = 1; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = [...]; public $parent = NULL; public $config_vars = [...]; public $ext = class Smarty_Internal_Extension_Handler { ... }; public $cache_id = NULL; public $compile_id = NULL; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = [...]; public $_cache = [...]; public $auto_literal = TRUE; public $error_unassigned = FALSE; public $use_include_path = FALSE; public $_templateDirNormalized = TRUE; public $_joined_template_dir = '/var/www/html/templates/#/var/www/html/plugins/themes/default/templates/'; public $_configDirNormalized = FALSE; public $_joined_config_dir = NULL; public $default_template_handler_func = NULL; public $default_config_handler_func = NULL; public $default_plugin_handler_func = NULL; public $_compileDirNormalized = TRUE; public $_pluginsDirNormalized = FALSE; public $_cacheDirNormalized = FALSE; public $force_compile = FALSE; public $use_sub_dirs = FALSE; public $allow_ambiguous_resources = FALSE; public $merge_compiled_includes = FALSE; public $extends_recursion = TRUE; public $force_cache = FALSE; public $left_delimiter = '{'; public $right_delimiter = '}'; public $literals = [...]; public $security_class = 'Smarty_Security'; public $security_policy = NULL; public $allow_php_templates = FALSE; public $debugging = FALSE; public $debugging_ctrl = 'NONE'; public $smarty_debug_id = 'SMARTY_DEBUG'; public $debug_tpl = NULL; public $error_reporting = 32757; public $config_overwrite = TRUE; public $config_booleanize = TRUE; public $config_read_hidden = FALSE; public $compile_locking = TRUE; public $cache_locking = FALSE; public $locking_timeout = 10; public $default_resource_type = 'app'; public $caching_type = 'file'; public $default_config_type = 'file'; public $cache_modified_check = FALSE; public $registered_plugins = [...]; public $registered_objects = [...]; public $registered_classes = [...]; public $registered_filters = [...]; public $registered_resources = [...]; public $registered_cache_resources = [...]; public $autoload_filters = [...]; public $default_modifiers = [...]; public $escape_html = FALSE; public $start_time = 1732446780.1848; public $_current_file = NULL; public $_parserdebug = FALSE; public $_debug = NULL; protected $template_dir = [...]; protected $_processedTemplateDir = [...]; protected $config_dir = '/var/www/html/cache/t_config'; protected $_processedConfigDir = [...]; protected $compile_dir = '/var/www/html/cache/t_compile/'; protected $plugins_dir = [...]; protected $cache_dir = '/var/www/html/cache/t_cache'; protected $obsoleteProperties = [...]; protected $accessMap = [...]; private ${Smarty}isMutingUndefinedOrNullWarnings = FALSE; private ${PKP\template\PKPTemplateManager}_styleSheets = [...]; private ${PKP\template\PKPTemplateManager}_javaScripts = [...]; private ${PKP\template\PKPTemplateManager}_htmlHeaders = [...]; private ${PKP\template\PKPTemplateManager}_constants = [...]; private ${PKP\template\PKPTemplateManager}_localeKeys = [...]; protected $_state = [...]; private ${PKP\template\PKPTemplateManager}_cacheability = 'no-store'; private ${PKP\template\PKPTemplateManager}_fbv = class PKP\form\FormBuilderVocabulary { ... }; private ${PKP\template\PKPTemplateManager}_request = class APP\core\Request { ... }; private array ${PKP\template\PKPTemplateManager}headers = [...]; private bool ${PKP\template\PKPTemplateManager}isBackendPage = FALSE }; public $config_vars = []; public $ext = class Smarty_Internal_Extension_Handler { public $objType = 2; private $_property_info = [...]; private $resolvedProperties = [...]; public $getTemplateVars = class Smarty_Internal_Method_GetTemplateVars { ... } }; public $cache_id = NULL; public $compile_id = '42362804174f266c598cdb32c3208fc745b92101'; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = []; public $_cache = []; public $smarty = class APP\template\TemplateManager { public $_objType = 1; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = [...]; public $parent = NULL; public $config_vars = [...]; public $ext = class Smarty_Internal_Extension_Handler { ... }; public $cache_id = NULL; public $compile_id = NULL; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = [...]; public $_cache = [...]; public $auto_literal = TRUE; public $error_unassigned = FALSE; public $use_include_path = FALSE; public $_templateDirNormalized = TRUE; public $_joined_template_dir = '/var/www/html/templates/#/var/www/html/plugins/themes/default/templates/'; public $_configDirNormalized = FALSE; public $_joined_config_dir = NULL; public $default_template_handler_func = NULL; public $default_config_handler_func = NULL; public $default_plugin_handler_func = NULL; public $_compileDirNormalized = TRUE; public $_pluginsDirNormalized = FALSE; public $_cacheDirNormalized = FALSE; public $force_compile = FALSE; public $use_sub_dirs = FALSE; public $allow_ambiguous_resources = FALSE; public $merge_compiled_includes = FALSE; public $extends_recursion = TRUE; public $force_cache = FALSE; public $left_delimiter = '{'; public $right_delimiter = '}'; public $literals = [...]; public $security_class = 'Smarty_Security'; public $security_policy = NULL; public $allow_php_templates = FALSE; public $debugging = FALSE; public $debugging_ctrl = 'NONE'; public $smarty_debug_id = 'SMARTY_DEBUG'; public $debug_tpl = NULL; public $error_reporting = 32757; public $config_overwrite = TRUE; public $config_booleanize = TRUE; public $config_read_hidden = FALSE; public $compile_locking = TRUE; public $cache_locking = FALSE; public $locking_timeout = 10; public $default_resource_type = 'app'; public $caching_type = 'file'; public $default_config_type = 'file'; public $cache_modified_check = FALSE; public $registered_plugins = [...]; public $registered_objects = [...]; public $registered_classes = [...]; public $registered_filters = [...]; public $registered_resources = [...]; public $registered_cache_resources = [...]; public $autoload_filters = [...]; public $default_modifiers = [...]; public $escape_html = FALSE; public $start_time = 1732446780.1848; public $_current_file = NULL; public $_parserdebug = FALSE; public $_debug = NULL; protected $template_dir = [...]; protected $_processedTemplateDir = [...]; protected $config_dir = '/var/www/html/cache/t_config'; protected $_processedConfigDir = [...]; protected $compile_dir = '/var/www/html/cache/t_compile/'; protected $plugins_dir = [...]; protected $cache_dir = '/var/www/html/cache/t_cache'; protected $obsoleteProperties = [...]; protected $accessMap = [...]; private ${Smarty}isMutingUndefinedOrNullWarnings = FALSE; private ${PKP\template\PKPTemplateManager}_styleSheets = [...]; private ${PKP\template\PKPTemplateManager}_javaScripts = [...]; private ${PKP\template\PKPTemplateManager}_htmlHeaders = [...]; private ${PKP\template\PKPTemplateManager}_constants = [...]; private ${PKP\template\PKPTemplateManager}_localeKeys = [...]; protected $_state = [...]; private ${PKP\template\PKPTemplateManager}_cacheability = 'no-store'; private ${PKP\template\PKPTemplateManager}_fbv = class PKP\form\FormBuilderVocabulary { ... }; private ${PKP\template\PKPTemplateManager}_request = class APP\core\Request { ... }; private array ${PKP\template\PKPTemplateManager}headers = [...]; private bool ${PKP\template\PKPTemplateManager}isBackendPage = FALSE }; public $source = class Smarty_Template_Source { public $uid = '1c372c95cd85572e0fbc9a53d0323a0b229cfc78'; public $resource = 'frontend/pages/article.tpl'; public $type = 'app'; public $name = 'frontend/pages/article.tpl'; public $filepath = 'app:frontendpagesarticle.tpl'; public $timestamp = 1724439197; public $exists = TRUE; public $basename = NULL; public $components = NULL; public $handler = class PKP\template\PKPTemplateResource { ... }; public $smarty = class APP\template\TemplateManager { ... }; public $isConfig = FALSE; public $content = NULL; public $compiler_class = 'Smarty_Internal_SmartyTemplateCompiler'; public $template_lexer_class = 'Smarty_Internal_Templatelexer'; public $template_parser_class = 'Smarty_Internal_Templateparser' }; public $inheritance = NULL; public $template_resource = 'frontend/pages/article.tpl'; public $mustCompile = FALSE; public $templateId = '/var/www/html/templates/#/var/www/html/plugins/themes/default/templates/#app:frontend/pages/article.tpl##42362804174f266c598cdb32c3208fc745b92101#0'; public $scope = 0; public $isRenderingCache = FALSE; public $startRenderCallbacks = []; public $endRenderCallbacks = []; public $compiled = class Smarty_Template_Compiled { public $filepath = '/var/www/html/cache/t_compile/42362804174f266c598cdb32c3208fc745b92101^1c372c95cd85572e0fbc9a53d0323a0b229cfc78_0.app.frontendpagesarticle.tpl.php'; public $timestamp = 1732299637; public $exists = TRUE; public $compile_id = NULL; public $processed = TRUE; public $unifunc = 'content_6740cb7558aae9_79447201'; public $has_nocache_code = FALSE; public $file_dependency = [...]; public $content = NULL; public $includes = [...]; public $isCache = FALSE; public $nocache_hash = NULL } } ).../smarty_template_resource_base.php:123
150.179824991616Smarty_Internal_Template->_subTemplateRender( $template = 'app:frontend/objects/article_details.tpl', $cache_id = NULL, $compile_id = '42362804174f266c598cdb32c3208fc745b92101', $caching = 0, $cache_lifetime = 3600, $data = [], $scope = 0, $forceTplCache = FALSE, $uid = ???, $content_func = ??? ).../42362804174f266c598cdb32c3208fc745b92101^1c372c95cd85572e0fbc9a53d0323a0b229cfc78_0.app.frontendpagesarticle.tpl.php:40
160.179824994040Smarty_Internal_Template->render( $no_output_filter = ???, $display = ??? ).../smarty_internal_template.php:386
170.179824994440Smarty_Template_Compiled->render( $_template = class Smarty_Internal_Template { public $_objType = 2; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = ['SCRIPT_NAME' => class Smarty_Variable { ... }, 'defaultCharset' => class Smarty_Variable { ... }, 'baseUrl' => class Smarty_Variable { ... }, 'currentContext' => class Smarty_Variable { ... }, 'currentLocale' => class Smarty_Variable { ... }, 'currentLocaleLangDir' => class Smarty_Variable { ... }, 'applicationName' => class Smarty_Variable { ... }, 'dateFormatShort' => class Smarty_Variable { ... }, 'dateFormatLong' => class Smarty_Variable { ... }, 'datetimeFormatShort' => class Smarty_Variable { ... }, 'datetimeFormatLong' => class Smarty_Variable { ... }, 'timeFormat' => class Smarty_Variable { ... }, 'displayPageHeaderTitle' => class Smarty_Variable { ... }, 'displayPageHeaderLogo' => class Smarty_Variable { ... }, 'displayPageHeaderLogoAltText' => class Smarty_Variable { ... }, 'activeTheme' => class Smarty_Variable { ... }, 'requestedPage' => class Smarty_Variable { ... }, 'requestedOp' => class Smarty_Variable { ... }, 'fbvStyles' => class Smarty_Variable { ... }, 'isUserLoggedIn' => class Smarty_Variable { ... }, 'isUserLoggedInAs' => class Smarty_Variable { ... }, 'itemsPerPage' => class Smarty_Variable { ... }, 'numPageLinks' => class Smarty_Variable { ... }, 'siteTitle' => class Smarty_Variable { ... }, 'hasSidebar' => class Smarty_Variable { ... }, 'brandImage' => class Smarty_Variable { ... }, 'sitePublicFilesDir' => class Smarty_Variable { ... }, 'publicFilesDir' => class Smarty_Variable { ... }, 'currentJournal' => class Smarty_Variable { ... }, 'primaryLocale' => class Smarty_Variable { ... }, 'supportedLocales' => class Smarty_Variable { ... }, 'enableAnnouncements' => class Smarty_Variable { ... }, 'disableUserReg' => class Smarty_Variable { ... }, 'pageFooter' => class Smarty_Variable { ... }, 'issue' => class Smarty_Variable { ... }, 'article' => class Smarty_Variable { ... }, 'publication' => class Smarty_Variable { ... }, 'currentPublication' => class Smarty_Variable { ... }, 'galley' => class Smarty_Variable { ... }, 'fileId' => class Smarty_Variable { ... }, 'submissionFileId' => class Smarty_Variable { ... }, 'userRoles' => class Smarty_Variable { ... }, 'firstPublication' => class Smarty_Variable { ... }, 'ccLicenseBadge' => class Smarty_Variable { ... }, 'section' => class Smarty_Variable { ... }, 'categories' => class Smarty_Variable { ... }, 'primaryGalleys' => class Smarty_Variable { ... }, 'supplementaryGalleys' => class Smarty_Variable { ... }, 'userGroupsById' => class Smarty_Variable { ... }, 'parsedCitations' => class Smarty_Variable { ... }, 'licenseTerms' => class Smarty_Variable { ... }, 'licenseUrl' => class Smarty_Variable { ... }, 'copyrightHolder' => class Smarty_Variable { ... }, 'copyrightYear' => class Smarty_Variable { ... }, 'pubIdPlugins' => class Smarty_Variable { ... }, 'keywords' => class Smarty_Variable { ... }, 'hasAccess' => class Smarty_Variable { ... }, 'citation' => class Smarty_Variable { ... }, 'citationArgs' => class Smarty_Variable { ... }, 'citationArgsJson' => class Smarty_Variable { ... }, 'citationStyles' => class Smarty_Variable { ... }, 'citationDownloads' => class Smarty_Variable { ... }, 'state' => class Smarty_Variable { ... }, 'heading' => class Smarty_Variable { ... }, 'author' => class Smarty_Variable { ... }, 'authorUserGroup' => class Smarty_Variable { ... }, 'doiObject' => class Smarty_Variable { ... }, 'doiUrl' => class Smarty_Variable { ... }, 'translatedDOI' => class Smarty_Variable { ... }, 'translatedKeywords' => class Smarty_Variable { ... }, 'keyword' => class Smarty_Variable { ... }, '__smarty_foreach_keywords' => class Smarty_Variable { ... }, 'hasBiographies' => class Smarty_Variable { ... }, 'authorName' => class Smarty_Variable { ... }, 'authorAffiliation' => class Smarty_Variable { ... }, 'pubIdPlugin' => class Smarty_Variable { ... }, 'pubId' => class Smarty_Variable { ... }, 'addThisProfileId' => class Smarty_Variable { ... }, 'addThisUsername' => class Smarty_Variable { ... }, 'addThisPassword' => class Smarty_Variable { ... }, 'addThisDisplayStyle' => class Smarty_Variable { ... }]; public $parent = class Smarty_Internal_Template { public $_objType = 2; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = [...]; public $parent = class APP\template\TemplateManager { ... }; public $config_vars = [...]; public $ext = class Smarty_Internal_Extension_Handler { ... }; public $cache_id = NULL; public $compile_id = '42362804174f266c598cdb32c3208fc745b92101'; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = [...]; public $_cache = [...]; public $smarty = class APP\template\TemplateManager { ... }; public $source = class Smarty_Template_Source { ... }; public $inheritance = NULL; public $template_resource = 'frontend/pages/article.tpl'; public $mustCompile = FALSE; public $templateId = '/var/www/html/templates/#/var/www/html/plugins/themes/default/templates/#app:frontend/pages/article.tpl##42362804174f266c598cdb32c3208fc745b92101#0'; public $scope = 0; public $isRenderingCache = FALSE; public $startRenderCallbacks = [...]; public $endRenderCallbacks = [...]; public $compiled = class Smarty_Template_Compiled { ... } }; public $config_vars = []; public $ext = class Smarty_Internal_Extension_Handler { public $objType = 2; private $_property_info = [...]; private $resolvedProperties = [...]; public $getTemplateVars = class Smarty_Internal_Method_GetTemplateVars { ... } }; public $cache_id = NULL; public $compile_id = '42362804174f266c598cdb32c3208fc745b92101'; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = []; public $_cache = []; public $smarty = class APP\template\TemplateManager { public $_objType = 1; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = [...]; public $parent = NULL; public $config_vars = [...]; public $ext = class Smarty_Internal_Extension_Handler { ... }; public $cache_id = NULL; public $compile_id = NULL; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = [...]; public $_cache = [...]; public $auto_literal = TRUE; public $error_unassigned = FALSE; public $use_include_path = FALSE; public $_templateDirNormalized = TRUE; public $_joined_template_dir = '/var/www/html/templates/#/var/www/html/plugins/themes/default/templates/'; public $_configDirNormalized = FALSE; public $_joined_config_dir = NULL; public $default_template_handler_func = NULL; public $default_config_handler_func = NULL; public $default_plugin_handler_func = NULL; public $_compileDirNormalized = TRUE; public $_pluginsDirNormalized = FALSE; public $_cacheDirNormalized = FALSE; public $force_compile = FALSE; public $use_sub_dirs = FALSE; public $allow_ambiguous_resources = FALSE; public $merge_compiled_includes = FALSE; public $extends_recursion = TRUE; public $force_cache = FALSE; public $left_delimiter = '{'; public $right_delimiter = '}'; public $literals = [...]; public $security_class = 'Smarty_Security'; public $security_policy = NULL; public $allow_php_templates = FALSE; public $debugging = FALSE; public $debugging_ctrl = 'NONE'; public $smarty_debug_id = 'SMARTY_DEBUG'; public $debug_tpl = NULL; public $error_reporting = 32757; public $config_overwrite = TRUE; public $config_booleanize = TRUE; public $config_read_hidden = FALSE; public $compile_locking = TRUE; public $cache_locking = FALSE; public $locking_timeout = 10; public $default_resource_type = 'app'; public $caching_type = 'file'; public $default_config_type = 'file'; public $cache_modified_check = FALSE; public $registered_plugins = [...]; public $registered_objects = [...]; public $registered_classes = [...]; public $registered_filters = [...]; public $registered_resources = [...]; public $registered_cache_resources = [...]; public $autoload_filters = [...]; public $default_modifiers = [...]; public $escape_html = FALSE; public $start_time = 1732446780.1848; public $_current_file = NULL; public $_parserdebug = FALSE; public $_debug = NULL; protected $template_dir = [...]; protected $_processedTemplateDir = [...]; protected $config_dir = '/var/www/html/cache/t_config'; protected $_processedConfigDir = [...]; protected $compile_dir = '/var/www/html/cache/t_compile/'; protected $plugins_dir = [...]; protected $cache_dir = '/var/www/html/cache/t_cache'; protected $obsoleteProperties = [...]; protected $accessMap = [...]; private ${Smarty}isMutingUndefinedOrNullWarnings = FALSE; private ${PKP\template\PKPTemplateManager}_styleSheets = [...]; private ${PKP\template\PKPTemplateManager}_javaScripts = [...]; private ${PKP\template\PKPTemplateManager}_htmlHeaders = [...]; private ${PKP\template\PKPTemplateManager}_constants = [...]; private ${PKP\template\PKPTemplateManager}_localeKeys = [...]; protected $_state = [...]; private ${PKP\template\PKPTemplateManager}_cacheability = 'no-store'; private ${PKP\template\PKPTemplateManager}_fbv = class PKP\form\FormBuilderVocabulary { ... }; private ${PKP\template\PKPTemplateManager}_request = class APP\core\Request { ... }; private array ${PKP\template\PKPTemplateManager}headers = [...]; private bool ${PKP\template\PKPTemplateManager}isBackendPage = FALSE }; public $source = class Smarty_Template_Source { public $uid = 'addd65021fadf964339ab08cd1aa93ba59b14e9c'; public $resource = 'app:frontend/objects/article_details.tpl'; public $type = 'app'; public $name = 'frontend/objects/article_details.tpl'; public $filepath = 'app:frontendobjectsarticle_details.tpl'; public $timestamp = 1724439197; public $exists = TRUE; public $basename = NULL; public $components = NULL; public $handler = class PKP\template\PKPTemplateResource { ... }; public $smarty = class APP\template\TemplateManager { ... }; public $isConfig = FALSE; public $content = NULL; public $compiler_class = 'Smarty_Internal_SmartyTemplateCompiler'; public $template_lexer_class = 'Smarty_Internal_Templatelexer'; public $template_parser_class = 'Smarty_Internal_Templateparser' }; public $inheritance = NULL; public $template_resource = 'app:frontend/objects/article_details.tpl'; public $mustCompile = FALSE; public $templateId = '36060c7c43ad1691e04870da0cec54c0d1263666'; public $scope = 0; public $isRenderingCache = FALSE; public $startRenderCallbacks = []; public $endRenderCallbacks = []; public $compiled = class Smarty_Template_Compiled { public $filepath = '/var/www/html/cache/t_compile/42362804174f266c598cdb32c3208fc745b92101^addd65021fadf964339ab08cd1aa93ba59b14e9c_0.app.frontendobjectsarticle_details.tpl.php'; public $timestamp = 1732299637; public $exists = TRUE; public $compile_id = NULL; public $processed = TRUE; public $unifunc = 'content_6740cb7578e617_99827455'; public $has_nocache_code = FALSE; public $file_dependency = [...]; public $content = NULL; public $includes = [...]; public $isCache = FALSE; public $nocache_hash = NULL } } ).../smarty_internal_template.php:217
180.180825145304Smarty_Template_Resource_Base->getRenderedTemplateCode( $_template = class Smarty_Internal_Template { public $_objType = 2; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = ['SCRIPT_NAME' => class Smarty_Variable { ... }, 'defaultCharset' => class Smarty_Variable { ... }, 'baseUrl' => class Smarty_Variable { ... }, 'currentContext' => class Smarty_Variable { ... }, 'currentLocale' => class Smarty_Variable { ... }, 'currentLocaleLangDir' => class Smarty_Variable { ... }, 'applicationName' => class Smarty_Variable { ... }, 'dateFormatShort' => class Smarty_Variable { ... }, 'dateFormatLong' => class Smarty_Variable { ... }, 'datetimeFormatShort' => class Smarty_Variable { ... }, 'datetimeFormatLong' => class Smarty_Variable { ... }, 'timeFormat' => class Smarty_Variable { ... }, 'displayPageHeaderTitle' => class Smarty_Variable { ... }, 'displayPageHeaderLogo' => class Smarty_Variable { ... }, 'displayPageHeaderLogoAltText' => class Smarty_Variable { ... }, 'activeTheme' => class Smarty_Variable { ... }, 'requestedPage' => class Smarty_Variable { ... }, 'requestedOp' => class Smarty_Variable { ... }, 'fbvStyles' => class Smarty_Variable { ... }, 'isUserLoggedIn' => class Smarty_Variable { ... }, 'isUserLoggedInAs' => class Smarty_Variable { ... }, 'itemsPerPage' => class Smarty_Variable { ... }, 'numPageLinks' => class Smarty_Variable { ... }, 'siteTitle' => class Smarty_Variable { ... }, 'hasSidebar' => class Smarty_Variable { ... }, 'brandImage' => class Smarty_Variable { ... }, 'sitePublicFilesDir' => class Smarty_Variable { ... }, 'publicFilesDir' => class Smarty_Variable { ... }, 'currentJournal' => class Smarty_Variable { ... }, 'primaryLocale' => class Smarty_Variable { ... }, 'supportedLocales' => class Smarty_Variable { ... }, 'enableAnnouncements' => class Smarty_Variable { ... }, 'disableUserReg' => class Smarty_Variable { ... }, 'pageFooter' => class Smarty_Variable { ... }, 'issue' => class Smarty_Variable { ... }, 'article' => class Smarty_Variable { ... }, 'publication' => class Smarty_Variable { ... }, 'currentPublication' => class Smarty_Variable { ... }, 'galley' => class Smarty_Variable { ... }, 'fileId' => class Smarty_Variable { ... }, 'submissionFileId' => class Smarty_Variable { ... }, 'userRoles' => class Smarty_Variable { ... }, 'firstPublication' => class Smarty_Variable { ... }, 'ccLicenseBadge' => class Smarty_Variable { ... }, 'section' => class Smarty_Variable { ... }, 'categories' => class Smarty_Variable { ... }, 'primaryGalleys' => class Smarty_Variable { ... }, 'supplementaryGalleys' => class Smarty_Variable { ... }, 'userGroupsById' => class Smarty_Variable { ... }, 'parsedCitations' => class Smarty_Variable { ... }, 'licenseTerms' => class Smarty_Variable { ... }, 'licenseUrl' => class Smarty_Variable { ... }, 'copyrightHolder' => class Smarty_Variable { ... }, 'copyrightYear' => class Smarty_Variable { ... }, 'pubIdPlugins' => class Smarty_Variable { ... }, 'keywords' => class Smarty_Variable { ... }, 'hasAccess' => class Smarty_Variable { ... }, 'citation' => class Smarty_Variable { ... }, 'citationArgs' => class Smarty_Variable { ... }, 'citationArgsJson' => class Smarty_Variable { ... }, 'citationStyles' => class Smarty_Variable { ... }, 'citationDownloads' => class Smarty_Variable { ... }, 'state' => class Smarty_Variable { ... }, 'heading' => class Smarty_Variable { ... }, 'author' => class Smarty_Variable { ... }, 'authorUserGroup' => class Smarty_Variable { ... }, 'doiObject' => class Smarty_Variable { ... }, 'doiUrl' => class Smarty_Variable { ... }, 'translatedDOI' => class Smarty_Variable { ... }, 'translatedKeywords' => class Smarty_Variable { ... }, 'keyword' => class Smarty_Variable { ... }, '__smarty_foreach_keywords' => class Smarty_Variable { ... }, 'hasBiographies' => class Smarty_Variable { ... }, 'authorName' => class Smarty_Variable { ... }, 'authorAffiliation' => class Smarty_Variable { ... }, 'pubIdPlugin' => class Smarty_Variable { ... }, 'pubId' => class Smarty_Variable { ... }, 'addThisProfileId' => class Smarty_Variable { ... }, 'addThisUsername' => class Smarty_Variable { ... }, 'addThisPassword' => class Smarty_Variable { ... }, 'addThisDisplayStyle' => class Smarty_Variable { ... }]; public $parent = class Smarty_Internal_Template { public $_objType = 2; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = [...]; public $parent = class APP\template\TemplateManager { ... }; public $config_vars = [...]; public $ext = class Smarty_Internal_Extension_Handler { ... }; public $cache_id = NULL; public $compile_id = '42362804174f266c598cdb32c3208fc745b92101'; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = [...]; public $_cache = [...]; public $smarty = class APP\template\TemplateManager { ... }; public $source = class Smarty_Template_Source { ... }; public $inheritance = NULL; public $template_resource = 'frontend/pages/article.tpl'; public $mustCompile = FALSE; public $templateId = '/var/www/html/templates/#/var/www/html/plugins/themes/default/templates/#app:frontend/pages/article.tpl##42362804174f266c598cdb32c3208fc745b92101#0'; public $scope = 0; public $isRenderingCache = FALSE; public $startRenderCallbacks = [...]; public $endRenderCallbacks = [...]; public $compiled = class Smarty_Template_Compiled { ... } }; public $config_vars = []; public $ext = class Smarty_Internal_Extension_Handler { public $objType = 2; private $_property_info = [...]; private $resolvedProperties = [...]; public $getTemplateVars = class Smarty_Internal_Method_GetTemplateVars { ... } }; public $cache_id = NULL; public $compile_id = '42362804174f266c598cdb32c3208fc745b92101'; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = []; public $_cache = []; public $smarty = class APP\template\TemplateManager { public $_objType = 1; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = [...]; public $parent = NULL; public $config_vars = [...]; public $ext = class Smarty_Internal_Extension_Handler { ... }; public $cache_id = NULL; public $compile_id = NULL; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = [...]; public $_cache = [...]; public $auto_literal = TRUE; public $error_unassigned = FALSE; public $use_include_path = FALSE; public $_templateDirNormalized = TRUE; public $_joined_template_dir = '/var/www/html/templates/#/var/www/html/plugins/themes/default/templates/'; public $_configDirNormalized = FALSE; public $_joined_config_dir = NULL; public $default_template_handler_func = NULL; public $default_config_handler_func = NULL; public $default_plugin_handler_func = NULL; public $_compileDirNormalized = TRUE; public $_pluginsDirNormalized = FALSE; public $_cacheDirNormalized = FALSE; public $force_compile = FALSE; public $use_sub_dirs = FALSE; public $allow_ambiguous_resources = FALSE; public $merge_compiled_includes = FALSE; public $extends_recursion = TRUE; public $force_cache = FALSE; public $left_delimiter = '{'; public $right_delimiter = '}'; public $literals = [...]; public $security_class = 'Smarty_Security'; public $security_policy = NULL; public $allow_php_templates = FALSE; public $debugging = FALSE; public $debugging_ctrl = 'NONE'; public $smarty_debug_id = 'SMARTY_DEBUG'; public $debug_tpl = NULL; public $error_reporting = 32757; public $config_overwrite = TRUE; public $config_booleanize = TRUE; public $config_read_hidden = FALSE; public $compile_locking = TRUE; public $cache_locking = FALSE; public $locking_timeout = 10; public $default_resource_type = 'app'; public $caching_type = 'file'; public $default_config_type = 'file'; public $cache_modified_check = FALSE; public $registered_plugins = [...]; public $registered_objects = [...]; public $registered_classes = [...]; public $registered_filters = [...]; public $registered_resources = [...]; public $registered_cache_resources = [...]; public $autoload_filters = [...]; public $default_modifiers = [...]; public $escape_html = FALSE; public $start_time = 1732446780.1848; public $_current_file = NULL; public $_parserdebug = FALSE; public $_debug = NULL; protected $template_dir = [...]; protected $_processedTemplateDir = [...]; protected $config_dir = '/var/www/html/cache/t_config'; protected $_processedConfigDir = [...]; protected $compile_dir = '/var/www/html/cache/t_compile/'; protected $plugins_dir = [...]; protected $cache_dir = '/var/www/html/cache/t_cache'; protected $obsoleteProperties = [...]; protected $accessMap = [...]; private ${Smarty}isMutingUndefinedOrNullWarnings = FALSE; private ${PKP\template\PKPTemplateManager}_styleSheets = [...]; private ${PKP\template\PKPTemplateManager}_javaScripts = [...]; private ${PKP\template\PKPTemplateManager}_htmlHeaders = [...]; private ${PKP\template\PKPTemplateManager}_constants = [...]; private ${PKP\template\PKPTemplateManager}_localeKeys = [...]; protected $_state = [...]; private ${PKP\template\PKPTemplateManager}_cacheability = 'no-store'; private ${PKP\template\PKPTemplateManager}_fbv = class PKP\form\FormBuilderVocabulary { ... }; private ${PKP\template\PKPTemplateManager}_request = class APP\core\Request { ... }; private array ${PKP\template\PKPTemplateManager}headers = [...]; private bool ${PKP\template\PKPTemplateManager}isBackendPage = FALSE }; public $source = class Smarty_Template_Source { public $uid = 'addd65021fadf964339ab08cd1aa93ba59b14e9c'; public $resource = 'app:frontend/objects/article_details.tpl'; public $type = 'app'; public $name = 'frontend/objects/article_details.tpl'; public $filepath = 'app:frontendobjectsarticle_details.tpl'; public $timestamp = 1724439197; public $exists = TRUE; public $basename = NULL; public $components = NULL; public $handler = class PKP\template\PKPTemplateResource { ... }; public $smarty = class APP\template\TemplateManager { ... }; public $isConfig = FALSE; public $content = NULL; public $compiler_class = 'Smarty_Internal_SmartyTemplateCompiler'; public $template_lexer_class = 'Smarty_Internal_Templatelexer'; public $template_parser_class = 'Smarty_Internal_Templateparser' }; public $inheritance = NULL; public $template_resource = 'app:frontend/objects/article_details.tpl'; public $mustCompile = FALSE; public $templateId = '36060c7c43ad1691e04870da0cec54c0d1263666'; public $scope = 0; public $isRenderingCache = FALSE; public $startRenderCallbacks = []; public $endRenderCallbacks = []; public $compiled = class Smarty_Template_Compiled { public $filepath = '/var/www/html/cache/t_compile/42362804174f266c598cdb32c3208fc745b92101^addd65021fadf964339ab08cd1aa93ba59b14e9c_0.app.frontendobjectsarticle_details.tpl.php'; public $timestamp = 1732299637; public $exists = TRUE; public $compile_id = NULL; public $processed = TRUE; public $unifunc = 'content_6740cb7578e617_99827455'; public $has_nocache_code = FALSE; public $file_dependency = [...]; public $content = NULL; public $includes = [...]; public $isCache = FALSE; public $nocache_hash = NULL } }, $unifunc = ??? ).../smarty_template_compiled.php:114
190.180925145304content_6740cb7578e617_99827455( $_smarty_tpl = class Smarty_Internal_Template { public $_objType = 2; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = ['SCRIPT_NAME' => class Smarty_Variable { ... }, 'defaultCharset' => class Smarty_Variable { ... }, 'baseUrl' => class Smarty_Variable { ... }, 'currentContext' => class Smarty_Variable { ... }, 'currentLocale' => class Smarty_Variable { ... }, 'currentLocaleLangDir' => class Smarty_Variable { ... }, 'applicationName' => class Smarty_Variable { ... }, 'dateFormatShort' => class Smarty_Variable { ... }, 'dateFormatLong' => class Smarty_Variable { ... }, 'datetimeFormatShort' => class Smarty_Variable { ... }, 'datetimeFormatLong' => class Smarty_Variable { ... }, 'timeFormat' => class Smarty_Variable { ... }, 'displayPageHeaderTitle' => class Smarty_Variable { ... }, 'displayPageHeaderLogo' => class Smarty_Variable { ... }, 'displayPageHeaderLogoAltText' => class Smarty_Variable { ... }, 'activeTheme' => class Smarty_Variable { ... }, 'requestedPage' => class Smarty_Variable { ... }, 'requestedOp' => class Smarty_Variable { ... }, 'fbvStyles' => class Smarty_Variable { ... }, 'isUserLoggedIn' => class Smarty_Variable { ... }, 'isUserLoggedInAs' => class Smarty_Variable { ... }, 'itemsPerPage' => class Smarty_Variable { ... }, 'numPageLinks' => class Smarty_Variable { ... }, 'siteTitle' => class Smarty_Variable { ... }, 'hasSidebar' => class Smarty_Variable { ... }, 'brandImage' => class Smarty_Variable { ... }, 'sitePublicFilesDir' => class Smarty_Variable { ... }, 'publicFilesDir' => class Smarty_Variable { ... }, 'currentJournal' => class Smarty_Variable { ... }, 'primaryLocale' => class Smarty_Variable { ... }, 'supportedLocales' => class Smarty_Variable { ... }, 'enableAnnouncements' => class Smarty_Variable { ... }, 'disableUserReg' => class Smarty_Variable { ... }, 'pageFooter' => class Smarty_Variable { ... }, 'issue' => class Smarty_Variable { ... }, 'article' => class Smarty_Variable { ... }, 'publication' => class Smarty_Variable { ... }, 'currentPublication' => class Smarty_Variable { ... }, 'galley' => class Smarty_Variable { ... }, 'fileId' => class Smarty_Variable { ... }, 'submissionFileId' => class Smarty_Variable { ... }, 'userRoles' => class Smarty_Variable { ... }, 'firstPublication' => class Smarty_Variable { ... }, 'ccLicenseBadge' => class Smarty_Variable { ... }, 'section' => class Smarty_Variable { ... }, 'categories' => class Smarty_Variable { ... }, 'primaryGalleys' => class Smarty_Variable { ... }, 'supplementaryGalleys' => class Smarty_Variable { ... }, 'userGroupsById' => class Smarty_Variable { ... }, 'parsedCitations' => class Smarty_Variable { ... }, 'licenseTerms' => class Smarty_Variable { ... }, 'licenseUrl' => class Smarty_Variable { ... }, 'copyrightHolder' => class Smarty_Variable { ... }, 'copyrightYear' => class Smarty_Variable { ... }, 'pubIdPlugins' => class Smarty_Variable { ... }, 'keywords' => class Smarty_Variable { ... }, 'hasAccess' => class Smarty_Variable { ... }, 'citation' => class Smarty_Variable { ... }, 'citationArgs' => class Smarty_Variable { ... }, 'citationArgsJson' => class Smarty_Variable { ... }, 'citationStyles' => class Smarty_Variable { ... }, 'citationDownloads' => class Smarty_Variable { ... }, 'state' => class Smarty_Variable { ... }, 'heading' => class Smarty_Variable { ... }, 'author' => class Smarty_Variable { ... }, 'authorUserGroup' => class Smarty_Variable { ... }, 'doiObject' => class Smarty_Variable { ... }, 'doiUrl' => class Smarty_Variable { ... }, 'translatedDOI' => class Smarty_Variable { ... }, 'translatedKeywords' => class Smarty_Variable { ... }, 'keyword' => class Smarty_Variable { ... }, '__smarty_foreach_keywords' => class Smarty_Variable { ... }, 'hasBiographies' => class Smarty_Variable { ... }, 'authorName' => class Smarty_Variable { ... }, 'authorAffiliation' => class Smarty_Variable { ... }, 'pubIdPlugin' => class Smarty_Variable { ... }, 'pubId' => class Smarty_Variable { ... }, 'addThisProfileId' => class Smarty_Variable { ... }, 'addThisUsername' => class Smarty_Variable { ... }, 'addThisPassword' => class Smarty_Variable { ... }, 'addThisDisplayStyle' => class Smarty_Variable { ... }]; public $parent = class Smarty_Internal_Template { public $_objType = 2; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = [...]; public $parent = class APP\template\TemplateManager { ... }; public $config_vars = [...]; public $ext = class Smarty_Internal_Extension_Handler { ... }; public $cache_id = NULL; public $compile_id = '42362804174f266c598cdb32c3208fc745b92101'; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = [...]; public $_cache = [...]; public $smarty = class APP\template\TemplateManager { ... }; public $source = class Smarty_Template_Source { ... }; public $inheritance = NULL; public $template_resource = 'frontend/pages/article.tpl'; public $mustCompile = FALSE; public $templateId = '/var/www/html/templates/#/var/www/html/plugins/themes/default/templates/#app:frontend/pages/article.tpl##42362804174f266c598cdb32c3208fc745b92101#0'; public $scope = 0; public $isRenderingCache = FALSE; public $startRenderCallbacks = [...]; public $endRenderCallbacks = [...]; public $compiled = class Smarty_Template_Compiled { ... } }; public $config_vars = []; public $ext = class Smarty_Internal_Extension_Handler { public $objType = 2; private $_property_info = [...]; private $resolvedProperties = [...]; public $getTemplateVars = class Smarty_Internal_Method_GetTemplateVars { ... } }; public $cache_id = NULL; public $compile_id = '42362804174f266c598cdb32c3208fc745b92101'; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = []; public $_cache = []; public $smarty = class APP\template\TemplateManager { public $_objType = 1; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = [...]; public $parent = NULL; public $config_vars = [...]; public $ext = class Smarty_Internal_Extension_Handler { ... }; public $cache_id = NULL; public $compile_id = NULL; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = [...]; public $_cache = [...]; public $auto_literal = TRUE; public $error_unassigned = FALSE; public $use_include_path = FALSE; public $_templateDirNormalized = TRUE; public $_joined_template_dir = '/var/www/html/templates/#/var/www/html/plugins/themes/default/templates/'; public $_configDirNormalized = FALSE; public $_joined_config_dir = NULL; public $default_template_handler_func = NULL; public $default_config_handler_func = NULL; public $default_plugin_handler_func = NULL; public $_compileDirNormalized = TRUE; public $_pluginsDirNormalized = FALSE; public $_cacheDirNormalized = FALSE; public $force_compile = FALSE; public $use_sub_dirs = FALSE; public $allow_ambiguous_resources = FALSE; public $merge_compiled_includes = FALSE; public $extends_recursion = TRUE; public $force_cache = FALSE; public $left_delimiter = '{'; public $right_delimiter = '}'; public $literals = [...]; public $security_class = 'Smarty_Security'; public $security_policy = NULL; public $allow_php_templates = FALSE; public $debugging = FALSE; public $debugging_ctrl = 'NONE'; public $smarty_debug_id = 'SMARTY_DEBUG'; public $debug_tpl = NULL; public $error_reporting = 32757; public $config_overwrite = TRUE; public $config_booleanize = TRUE; public $config_read_hidden = FALSE; public $compile_locking = TRUE; public $cache_locking = FALSE; public $locking_timeout = 10; public $default_resource_type = 'app'; public $caching_type = 'file'; public $default_config_type = 'file'; public $cache_modified_check = FALSE; public $registered_plugins = [...]; public $registered_objects = [...]; public $registered_classes = [...]; public $registered_filters = [...]; public $registered_resources = [...]; public $registered_cache_resources = [...]; public $autoload_filters = [...]; public $default_modifiers = [...]; public $escape_html = FALSE; public $start_time = 1732446780.1848; public $_current_file = NULL; public $_parserdebug = FALSE; public $_debug = NULL; protected $template_dir = [...]; protected $_processedTemplateDir = [...]; protected $config_dir = '/var/www/html/cache/t_config'; protected $_processedConfigDir = [...]; protected $compile_dir = '/var/www/html/cache/t_compile/'; protected $plugins_dir = [...]; protected $cache_dir = '/var/www/html/cache/t_cache'; protected $obsoleteProperties = [...]; protected $accessMap = [...]; private ${Smarty}isMutingUndefinedOrNullWarnings = FALSE; private ${PKP\template\PKPTemplateManager}_styleSheets = [...]; private ${PKP\template\PKPTemplateManager}_javaScripts = [...]; private ${PKP\template\PKPTemplateManager}_htmlHeaders = [...]; private ${PKP\template\PKPTemplateManager}_constants = [...]; private ${PKP\template\PKPTemplateManager}_localeKeys = [...]; protected $_state = [...]; private ${PKP\template\PKPTemplateManager}_cacheability = 'no-store'; private ${PKP\template\PKPTemplateManager}_fbv = class PKP\form\FormBuilderVocabulary { ... }; private ${PKP\template\PKPTemplateManager}_request = class APP\core\Request { ... }; private array ${PKP\template\PKPTemplateManager}headers = [...]; private bool ${PKP\template\PKPTemplateManager}isBackendPage = FALSE }; public $source = class Smarty_Template_Source { public $uid = 'addd65021fadf964339ab08cd1aa93ba59b14e9c'; public $resource = 'app:frontend/objects/article_details.tpl'; public $type = 'app'; public $name = 'frontend/objects/article_details.tpl'; public $filepath = 'app:frontendobjectsarticle_details.tpl'; public $timestamp = 1724439197; public $exists = TRUE; public $basename = NULL; public $components = NULL; public $handler = class PKP\template\PKPTemplateResource { ... }; public $smarty = class APP\template\TemplateManager { ... }; public $isConfig = FALSE; public $content = NULL; public $compiler_class = 'Smarty_Internal_SmartyTemplateCompiler'; public $template_lexer_class = 'Smarty_Internal_Templatelexer'; public $template_parser_class = 'Smarty_Internal_Templateparser' }; public $inheritance = NULL; public $template_resource = 'app:frontend/objects/article_details.tpl'; public $mustCompile = FALSE; public $templateId = '36060c7c43ad1691e04870da0cec54c0d1263666'; public $scope = 0; public $isRenderingCache = FALSE; public $startRenderCallbacks = []; public $endRenderCallbacks = []; public $compiled = class Smarty_Template_Compiled { public $filepath = '/var/www/html/cache/t_compile/42362804174f266c598cdb32c3208fc745b92101^addd65021fadf964339ab08cd1aa93ba59b14e9c_0.app.frontendobjectsarticle_details.tpl.php'; public $timestamp = 1732299637; public $exists = TRUE; public $compile_id = NULL; public $processed = TRUE; public $unifunc = 'content_6740cb7578e617_99827455'; public $has_nocache_code = FALSE; public $file_dependency = [...]; public $content = NULL; public $includes = [...]; public $isCache = FALSE; public $nocache_hash = NULL } } ).../smarty_template_resource_base.php:123
200.187825236640PKP\template\PKPTemplateManager->smartyCallHook( $params = ['name' => 'Templates::Article::Details'], $smarty = class Smarty_Internal_Template { public $_objType = 2; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = ['SCRIPT_NAME' => class Smarty_Variable { ... }, 'defaultCharset' => class Smarty_Variable { ... }, 'baseUrl' => class Smarty_Variable { ... }, 'currentContext' => class Smarty_Variable { ... }, 'currentLocale' => class Smarty_Variable { ... }, 'currentLocaleLangDir' => class Smarty_Variable { ... }, 'applicationName' => class Smarty_Variable { ... }, 'dateFormatShort' => class Smarty_Variable { ... }, 'dateFormatLong' => class Smarty_Variable { ... }, 'datetimeFormatShort' => class Smarty_Variable { ... }, 'datetimeFormatLong' => class Smarty_Variable { ... }, 'timeFormat' => class Smarty_Variable { ... }, 'displayPageHeaderTitle' => class Smarty_Variable { ... }, 'displayPageHeaderLogo' => class Smarty_Variable { ... }, 'displayPageHeaderLogoAltText' => class Smarty_Variable { ... }, 'activeTheme' => class Smarty_Variable { ... }, 'requestedPage' => class Smarty_Variable { ... }, 'requestedOp' => class Smarty_Variable { ... }, 'fbvStyles' => class Smarty_Variable { ... }, 'isUserLoggedIn' => class Smarty_Variable { ... }, 'isUserLoggedInAs' => class Smarty_Variable { ... }, 'itemsPerPage' => class Smarty_Variable { ... }, 'numPageLinks' => class Smarty_Variable { ... }, 'siteTitle' => class Smarty_Variable { ... }, 'hasSidebar' => class Smarty_Variable { ... }, 'brandImage' => class Smarty_Variable { ... }, 'sitePublicFilesDir' => class Smarty_Variable { ... }, 'publicFilesDir' => class Smarty_Variable { ... }, 'currentJournal' => class Smarty_Variable { ... }, 'primaryLocale' => class Smarty_Variable { ... }, 'supportedLocales' => class Smarty_Variable { ... }, 'enableAnnouncements' => class Smarty_Variable { ... }, 'disableUserReg' => class Smarty_Variable { ... }, 'pageFooter' => class Smarty_Variable { ... }, 'issue' => class Smarty_Variable { ... }, 'article' => class Smarty_Variable { ... }, 'publication' => class Smarty_Variable { ... }, 'currentPublication' => class Smarty_Variable { ... }, 'galley' => class Smarty_Variable { ... }, 'fileId' => class Smarty_Variable { ... }, 'submissionFileId' => class Smarty_Variable { ... }, 'userRoles' => class Smarty_Variable { ... }, 'firstPublication' => class Smarty_Variable { ... }, 'ccLicenseBadge' => class Smarty_Variable { ... }, 'section' => class Smarty_Variable { ... }, 'categories' => class Smarty_Variable { ... }, 'primaryGalleys' => class Smarty_Variable { ... }, 'supplementaryGalleys' => class Smarty_Variable { ... }, 'userGroupsById' => class Smarty_Variable { ... }, 'parsedCitations' => class Smarty_Variable { ... }, 'licenseTerms' => class Smarty_Variable { ... }, 'licenseUrl' => class Smarty_Variable { ... }, 'copyrightHolder' => class Smarty_Variable { ... }, 'copyrightYear' => class Smarty_Variable { ... }, 'pubIdPlugins' => class Smarty_Variable { ... }, 'keywords' => class Smarty_Variable { ... }, 'hasAccess' => class Smarty_Variable { ... }, 'citation' => class Smarty_Variable { ... }, 'citationArgs' => class Smarty_Variable { ... }, 'citationArgsJson' => class Smarty_Variable { ... }, 'citationStyles' => class Smarty_Variable { ... }, 'citationDownloads' => class Smarty_Variable { ... }, 'state' => class Smarty_Variable { ... }, 'heading' => class Smarty_Variable { ... }, 'author' => class Smarty_Variable { ... }, 'authorUserGroup' => class Smarty_Variable { ... }, 'doiObject' => class Smarty_Variable { ... }, 'doiUrl' => class Smarty_Variable { ... }, 'translatedDOI' => class Smarty_Variable { ... }, 'translatedKeywords' => class Smarty_Variable { ... }, 'keyword' => class Smarty_Variable { ... }, '__smarty_foreach_keywords' => class Smarty_Variable { ... }, 'hasBiographies' => class Smarty_Variable { ... }, 'authorName' => class Smarty_Variable { ... }, 'authorAffiliation' => class Smarty_Variable { ... }, 'pubIdPlugin' => class Smarty_Variable { ... }, 'pubId' => class Smarty_Variable { ... }, 'addThisProfileId' => class Smarty_Variable { ... }, 'addThisUsername' => class Smarty_Variable { ... }, 'addThisPassword' => class Smarty_Variable { ... }, 'addThisDisplayStyle' => class Smarty_Variable { ... }]; public $parent = class Smarty_Internal_Template { public $_objType = 2; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = [...]; public $parent = class APP\template\TemplateManager { ... }; public $config_vars = [...]; public $ext = class Smarty_Internal_Extension_Handler { ... }; public $cache_id = NULL; public $compile_id = '42362804174f266c598cdb32c3208fc745b92101'; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = [...]; public $_cache = [...]; public $smarty = class APP\template\TemplateManager { ... }; public $source = class Smarty_Template_Source { ... }; public $inheritance = NULL; public $template_resource = 'frontend/pages/article.tpl'; public $mustCompile = FALSE; public $templateId = '/var/www/html/templates/#/var/www/html/plugins/themes/default/templates/#app:frontend/pages/article.tpl##42362804174f266c598cdb32c3208fc745b92101#0'; public $scope = 0; public $isRenderingCache = FALSE; public $startRenderCallbacks = [...]; public $endRenderCallbacks = [...]; public $compiled = class Smarty_Template_Compiled { ... } }; public $config_vars = []; public $ext = class Smarty_Internal_Extension_Handler { public $objType = 2; private $_property_info = [...]; private $resolvedProperties = [...]; public $getTemplateVars = class Smarty_Internal_Method_GetTemplateVars { ... } }; public $cache_id = NULL; public $compile_id = '42362804174f266c598cdb32c3208fc745b92101'; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = []; public $_cache = []; public $smarty = class APP\template\TemplateManager { public $_objType = 1; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = [...]; public $parent = NULL; public $config_vars = [...]; public $ext = class Smarty_Internal_Extension_Handler { ... }; public $cache_id = NULL; public $compile_id = NULL; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = [...]; public $_cache = [...]; public $auto_literal = TRUE; public $error_unassigned = FALSE; public $use_include_path = FALSE; public $_templateDirNormalized = TRUE; public $_joined_template_dir = '/var/www/html/templates/#/var/www/html/plugins/themes/default/templates/'; public $_configDirNormalized = FALSE; public $_joined_config_dir = NULL; public $default_template_handler_func = NULL; public $default_config_handler_func = NULL; public $default_plugin_handler_func = NULL; public $_compileDirNormalized = TRUE; public $_pluginsDirNormalized = FALSE; public $_cacheDirNormalized = FALSE; public $force_compile = FALSE; public $use_sub_dirs = FALSE; public $allow_ambiguous_resources = FALSE; public $merge_compiled_includes = FALSE; public $extends_recursion = TRUE; public $force_cache = FALSE; public $left_delimiter = '{'; public $right_delimiter = '}'; public $literals = [...]; public $security_class = 'Smarty_Security'; public $security_policy = NULL; public $allow_php_templates = FALSE; public $debugging = FALSE; public $debugging_ctrl = 'NONE'; public $smarty_debug_id = 'SMARTY_DEBUG'; public $debug_tpl = NULL; public $error_reporting = 32757; public $config_overwrite = TRUE; public $config_booleanize = TRUE; public $config_read_hidden = FALSE; public $compile_locking = TRUE; public $cache_locking = FALSE; public $locking_timeout = 10; public $default_resource_type = 'app'; public $caching_type = 'file'; public $default_config_type = 'file'; public $cache_modified_check = FALSE; public $registered_plugins = [...]; public $registered_objects = [...]; public $registered_classes = [...]; public $registered_filters = [...]; public $registered_resources = [...]; public $registered_cache_resources = [...]; public $autoload_filters = [...]; public $default_modifiers = [...]; public $escape_html = FALSE; public $start_time = 1732446780.1848; public $_current_file = NULL; public $_parserdebug = FALSE; public $_debug = NULL; protected $template_dir = [...]; protected $_processedTemplateDir = [...]; protected $config_dir = '/var/www/html/cache/t_config'; protected $_processedConfigDir = [...]; protected $compile_dir = '/var/www/html/cache/t_compile/'; protected $plugins_dir = [...]; protected $cache_dir = '/var/www/html/cache/t_cache'; protected $obsoleteProperties = [...]; protected $accessMap = [...]; private ${Smarty}isMutingUndefinedOrNullWarnings = FALSE; private ${PKP\template\PKPTemplateManager}_styleSheets = [...]; private ${PKP\template\PKPTemplateManager}_javaScripts = [...]; private ${PKP\template\PKPTemplateManager}_htmlHeaders = [...]; private ${PKP\template\PKPTemplateManager}_constants = [...]; private ${PKP\template\PKPTemplateManager}_localeKeys = [...]; protected $_state = [...]; private ${PKP\template\PKPTemplateManager}_cacheability = 'no-store'; private ${PKP\template\PKPTemplateManager}_fbv = class PKP\form\FormBuilderVocabulary { ... }; private ${PKP\template\PKPTemplateManager}_request = class APP\core\Request { ... }; private array ${PKP\template\PKPTemplateManager}headers = [...]; private bool ${PKP\template\PKPTemplateManager}isBackendPage = FALSE }; public $source = class Smarty_Template_Source { public $uid = 'addd65021fadf964339ab08cd1aa93ba59b14e9c'; public $resource = 'app:frontend/objects/article_details.tpl'; public $type = 'app'; public $name = 'frontend/objects/article_details.tpl'; public $filepath = 'app:frontendobjectsarticle_details.tpl'; public $timestamp = 1724439197; public $exists = TRUE; public $basename = NULL; public $components = NULL; public $handler = class PKP\template\PKPTemplateResource { ... }; public $smarty = class APP\template\TemplateManager { ... }; public $isConfig = FALSE; public $content = NULL; public $compiler_class = 'Smarty_Internal_SmartyTemplateCompiler'; public $template_lexer_class = 'Smarty_Internal_Templatelexer'; public $template_parser_class = 'Smarty_Internal_Templateparser' }; public $inheritance = NULL; public $template_resource = 'app:frontend/objects/article_details.tpl'; public $mustCompile = FALSE; public $templateId = '36060c7c43ad1691e04870da0cec54c0d1263666'; public $scope = 0; public $isRenderingCache = FALSE; public $startRenderCallbacks = []; public $endRenderCallbacks = []; public $compiled = class Smarty_Template_Compiled { public $filepath = '/var/www/html/cache/t_compile/42362804174f266c598cdb32c3208fc745b92101^addd65021fadf964339ab08cd1aa93ba59b14e9c_0.app.frontendobjectsarticle_details.tpl.php'; public $timestamp = 1732299637; public $exists = TRUE; public $compile_id = NULL; public $processed = TRUE; public $unifunc = 'content_6740cb7578e617_99827455'; public $has_nocache_code = FALSE; public $file_dependency = [...]; public $content = NULL; public $includes = [...]; public $isCache = FALSE; public $nocache_hash = NULL } } ).../42362804174f266c598cdb32c3208fc745b92101^addd65021fadf964339ab08cd1aa93ba59b14e9c_0.app.frontendobjectsarticle_details.tpl.php:560
210.187825237080PKP\plugins\Hook::call( $hookName = 'Templates::Article::Details', $args = [0 => ['name' => 'Templates::Article::Details'], 1 => class Smarty_Internal_Template { public $_objType = 2; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = [...]; public $parent = class Smarty_Internal_Template { ... }; public $config_vars = [...]; public $ext = class Smarty_Internal_Extension_Handler { ... }; public $cache_id = NULL; public $compile_id = '42362804174f266c598cdb32c3208fc745b92101'; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = [...]; public $_cache = [...]; public $smarty = class APP\template\TemplateManager { ... }; public $source = class Smarty_Template_Source { ... }; public $inheritance = NULL; public $template_resource = 'app:frontend/objects/article_details.tpl'; public $mustCompile = FALSE; public $templateId = '36060c7c43ad1691e04870da0cec54c0d1263666'; public $scope = 0; public $isRenderingCache = FALSE; public $startRenderCallbacks = [...]; public $endRenderCallbacks = [...]; public $compiled = class Smarty_Template_Compiled { ... } }, 2 => '\t<div class="item citation">\n\t\t<section class="sub_item citation_display">\n\t\t\t<h2 class="label">\n\t\t\t\tCómo citar\n\t\t\t</h2>\n\t\t\t<div class="value">\n\t\t\t\t<div id="citationOutput" role="region" aria-live="polite">\n\t\t\t\t\t<div class="csl-bib-body">\n <div class="csl-entry"><div class="csl-left-margin">1.</div><div class="csl-right-inline">Novas tecnologias para estudo da tuberculose: Uma análise da detecção e transmissão de M. tuberculosis circulante. Com. Ciências Saúde [Internet]. 2018 Feb. 9 [cited 2024 Nov'...] ).../PKPTemplateManager.php:1784
220.187825237456PKP\plugins\Hook::run( $hookName = 'Templates::Article::Details', $args = [0 => [0 => [...], 1 => class Smarty_Internal_Template { ... }, 2 => '\t<div class="item citation">\n\t\t<section class="sub_item citation_display">\n\t\t\t<h2 class="label">\n\t\t\t\tCómo citar\n\t\t\t</h2>\n\t\t\t<div class="value">\n\t\t\t\t<div id="citationOutput" role="region" aria-live="polite">\n\t\t\t\t\t<div class="csl-bib-body">\n <div class="csl-entry"><div class="csl-left-margin">1.</div><div class="csl-right-inline">Novas tecnologias para estudo da tuberculose: Uma análise da detecção e transmissão de M. tuberculosis circulante. Com. Ciências Saúde [Internet]. 2018 Feb. 9 [cited 2024 Nov'...]] ).../Hook.php:113
230.188525286416call_user_func_array:{/var/www/html/lib/pkp/classes/plugins/Hook.php:139}( $callback = [0 => class APP\plugins\generic\citations\CitationsPlugin { public $pluginPath = 'plugins/generic/citations'; public $pluginCategory = 'generic'; public $request = NULL }, 1 => 'citationsContent'], $args = [0 => 'Templates::Article::Details', 1 => [0 => [...], 1 => class Smarty_Internal_Template { ... }, 2 => '\t<div class="item citation">\n\t\t<section class="sub_item citation_display">\n\t\t\t<h2 class="label">\n\t\t\t\tCómo citar\n\t\t\t</h2>\n\t\t\t<div class="value">\n\t\t\t\t<div id="citationOutput" role="region" aria-live="polite">\n\t\t\t\t\t<div class="csl-bib-body">\n <div class="csl-entry"><div class="csl-left-margin">1.</div><div class="csl-right-inline">Novas tecnologias para estudo da tuberculose: Uma análise da detecção e transmissão de M. tuberculosis circulante. Com. Ciências Saúde [Internet]. 2018 Feb. 9 [cited 2024 Nov'...]] ).../Hook.php:139
240.188525286744APP\plugins\generic\citations\CitationsPlugin->citationsContent( $hookName = 'Templates::Article::Details', $args = [0 => ['name' => 'Templates::Article::Details'], 1 => class Smarty_Internal_Template { public $_objType = 2; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = [...]; public $parent = class Smarty_Internal_Template { ... }; public $config_vars = [...]; public $ext = class Smarty_Internal_Extension_Handler { ... }; public $cache_id = NULL; public $compile_id = '42362804174f266c598cdb32c3208fc745b92101'; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = [...]; public $_cache = [...]; public $smarty = class APP\template\TemplateManager { ... }; public $source = class Smarty_Template_Source { ... }; public $inheritance = NULL; public $template_resource = 'app:frontend/objects/article_details.tpl'; public $mustCompile = FALSE; public $templateId = '36060c7c43ad1691e04870da0cec54c0d1263666'; public $scope = 0; public $isRenderingCache = FALSE; public $startRenderCallbacks = [...]; public $endRenderCallbacks = [...]; public $compiled = class Smarty_Template_Compiled { ... } }, 2 => '\t<div class="item citation">\n\t\t<section class="sub_item citation_display">\n\t\t\t<h2 class="label">\n\t\t\t\tCómo citar\n\t\t\t</h2>\n\t\t\t<div class="value">\n\t\t\t\t<div id="citationOutput" role="region" aria-live="polite">\n\t\t\t\t\t<div class="csl-bib-body">\n <div class="csl-entry"><div class="csl-left-margin">1.</div><div class="csl-right-inline">Novas tecnologias para estudo da tuberculose: Uma análise da detecção e transmissão de M. tuberculosis circulante. Com. Ciências Saúde [Internet]. 2018 Feb. 9 [cited 2024 Nov'...] ).../Hook.php:139
250.188525287584json_decode( $json = NULL, $associative = TRUE ).../CitationsPlugin.php:68

Cómo citar

1.
Novas tecnologias para estudo da tuberculose: Uma análise da detecção e transmissão de M. tuberculosis circulante. Com. Ciências Saúde [Internet]. 2018 Feb. 9 [cited 2024 Nov. 24];28(01):85-90. Available from: https://revistaccs.espdf.fepecs.edu.br/index.php/comunicacaoemcienciasdasaude/article/view/124

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