The variation of BCG vaccine efficacy justifies a second dose?

An integrative review

Authors

DOI:

https://doi.org/10.51723/ccs.v33i01.942

Keywords:

BCG Vaccine, Tuberculosis, Secondary Immunization, Vaccination

Abstract

Aims: analyze effectiveness of BCG vaccine, the possibility of applying a second dose and new tuberculose prevention strategies. Method: integrative review. Selection of articles in BVS, Lilacs and MEDLINE databases and use of descriptors ‘BCG Vaccine’ AND ‘Tuberculosis’ AND ‘Secondary Immunization’ AND ‘Vaccination’. The choice of articles went through filter application, title and abstract analysis, and full reading, resulting in 14 articles. Results: for an alternative to improve the performance of the single dose, there are boosters and revaccination. Conclusion: it is necessary to develop further studies on the applicability of the second dose considering geoeconomic factors. For now, WHO does not recommend this practice.

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Author Biographies

  • Giovana Knapik Batista, Faculdades Pequeno Príncipe

    Estudante do Curso de Graduação em Medicina. Faculdades Pequeno Príncipe, Curitiba, Paraná, Brasil

  • Oona Salomão Erdmann, Faculdades Pequeno Príncipe

    Estudante do Curso de Graduação em Medicina. Faculdades Pequeno Príncipe, Curitiba, Paraná, Brasil

  • Alanis Carolina Guimarães, Faculdades Pequeno Príncipe

    Estudante do Curso de Graduação em Medicina. Faculdades Pequeno Príncipe, Curitiba, Paraná, Brasil

  • Matheus Corrêa, Faculdades Pequeno Príncipe

    Estudante do Curso de Graduação em Medicina. Faculdades Pequeno Príncipe, Curitiba, Paraná, Brasil

  • Thayná Vitória Zazzera de Moraes, Faculdades Pequeno Príncipe

    Estudante do Curso de Graduação em Medicina. Faculdades Pequeno Príncipe, Curitiba, Paraná, Brasil

  • Laercio Dante Stein Piancini, Faculdades Pequeno Príncipe

    Mestre e Doutor em Genética. Graduado em Ciências Biológicas pela Universidade Federal do Paraná. Docente no curso de Medicina das Faculdades Pequeno Príncipe, Curitiba, Paraná, Brasil.

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Published

2022-03-11

Issue

Section

Clínica Assistencial

How to Cite

1.
The variation of BCG vaccine efficacy justifies a second dose? : An integrative review. Com. Ciências Saúde [Internet]. 2022 Mar. 11 [cited 2024 Nov. 20];33(01). Available from: https://revistaccs.espdf.fepecs.edu.br/index.php/comunicacaoemcienciasdasaude/article/view/942