Development of Rapid and Low Cost Analytical Methods for the Quality Control of Antidiabetic Medications Used in Brazil in the Unified Health System

Authors

  • Paulo Roberto da Silva Ribeiro Universidade Federal do Maranhão

DOI:

https://doi.org/10.51723/ccs.v28i01.114

Keywords:

Analytical Methods, Quality Control, Antidiabetic Medicines, Unified Health System

Abstract

Diabetes Mellitus (DM) is a global epidemic, which represents a serious challenge for the public health system. One of the measures to maintain the normal glycemic level and reduce morbidity and mortality due to DM is the use of antidiabetic medicines such as glibenclamide (GLB) and gliclazide (GLZ). This work aimed at the development of unpublished, simple, fast, reliable and low cost analytical methods for the spectrophotometric determination of GLB and GLZ content in pharmaceutical formulations. Qualitative tests were performed from GLB and GLZ with Eosin (EOS). The formation of optically stable colored compounds with maximum absorption at 545 and 543 nm, respectively, was observed. Under optimized experimental conditions, analytical curves were obtained by relating the GLB and GLZ concentrations to the equivalent absorbances against the corresponding reagent blank. The proposed methods are based on the formation of binary, colored and highly stable complexes between investigated drugs and EOS. When
applied to the GLB and GLZ assay contained in commercial samples, the results showed that there were no significant differences between the proposed methods and the official methods. The accomplishment of this work was of paramount importance, since it allowed the development of unpublished, precise, accurate, reliable, simpler, faster, more versatile
analytical methods with greater economic feasibility (low cost). These methods can be used in routine analyzes for the quality control of antidiabetic drugs (GLB and GLZ) present in medicines consumed in Brazil.

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Author Biography

  • Paulo Roberto da Silva Ribeiro, Universidade Federal do Maranhão

    Núcleo de Pesquisas em Ciências Farmacêuticas e Química Analítica Aplicada (NUPFARQ), Centro de Ciências
    Sociais, Saúde e Tecnologia (CCSST), Universidade Federal do Maranhão(UFMA) CEP 65.900-410

    Rua Urbano Santos, s/n, Centro, Imperatriz– MA – CEP: 65.900-410. Telefone: (99) 3529-6068

References

1. Hisham EA. Spectrophotometric and spectrofluorimetric methods for the determination of ramipril in its pure and dosage form. Spectrochim. Acta A Mol. Biomol. Spectrosc. 2007; 66(3): 701-6.
2. IDF – International Diabetes Federation. Global Guideline for Managing Older People with Type 2 Diabetes. Brussels: IDF Belgium; 2013.
3. Farmacopeia Brasileira. Agência Nacional de Vigilância Sanitária. Brasília: ANVISA, Fundação
Oswaldo Cruz., 5ª Ed., v. 2, 2010.

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Published

2018-02-02

Issue

Vol. 28 No. 01 (2017): CCS

Section

Clínica Assistencial

License

Declaro para os devidos fins que o artigo que estou submetendo representa um trabalho original e nunca foi publicado total ou parcialmente, e que se alguma de suas partes foi publicada possuímos autorização expressa para a publicação no periódico Comunicação em Ciências da Saúde (CCS). Esse artigo não foi enviado a outro periódico e não o será enquanto estiver sendo considerada sua publicação; caso venha a ser aceito não será publicado em outro periódico; e não contém material difamatório ou ilegal sob nenhuma forma, não viola a intimidade de terceiros, nem infringe direitos protegidos.

Eu e demais autores desse trabalho certificamos por meio desta declaração que:

  • Concordamos com as normas editoriais e com o processo de revisão da CCS;
  • Aceitamos a responsabilidade pela conduta desse estudo e pela análise e interpretação dos dados;
  • Cooperaremos, sempre que solicitado, na obtenção e fornecimento de dados sobre os quais o manuscrito está baseado, para exame dos avaliadores;
  • Não estão sendo omitidos quaisquer ligações ou acordos de financiamento entre os autores e companhias ou pessoas que possam ter interesse no material abordado no artigo;
  • Não estão sendo excluídos ou omitidos deste artigo autores ou instituições participantes;
  • Possuímos permissão para uso de figuras e tabelas publicadas em outras fontes;
  • Possuímos permissão das pessoas e instituições citadas nos agradecimentos;
  • O autor correspondente autoriza a publicação do endereço informado e e-mail do(s) autor(es) junto com o artigo;
  • Assumimos a responsabilidade pela entrega de documentos verídicos;
  • Autorizamos a publicação do referido artigo no periódico Comunicação em Ciências da Saúde, segundo critérios próprios e em número e volume a serem definidos pelo editor do periódico;
  • Nos comprometemos a atender os prazos estipulados pelos editores do periódico Comunicação em Ciências da saúde;
  • Estamos cientes de que a não manifestação no prazo de dois dias da revisão da diagramação, recebida por e-mail, será considerado aprovado para publicação.

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public $template_lexer_class = 'Smarty_Internal_Templatelexer'; public $template_parser_class = 'Smarty_Internal_Templateparser' }; public $inheritance = NULL; public $template_resource = 'frontend/pages/article.tpl'; public $mustCompile = FALSE; public $templateId = '/var/www/html/templates/#/var/www/html/plugins/themes/default/templates/#app:frontend/pages/article.tpl##42362804174f266c598cdb32c3208fc745b92101#0'; public $scope = 0; public $isRenderingCache = FALSE; public $startRenderCallbacks = []; public $endRenderCallbacks = []; public $compiled = class Smarty_Template_Compiled { public $filepath = '/var/www/html/cache/t_compile/42362804174f266c598cdb32c3208fc745b92101^1c372c95cd85572e0fbc9a53d0323a0b229cfc78_0.app.frontendpagesarticle.tpl.php'; public $timestamp = 1732299637; public $exists = TRUE; public $compile_id = NULL; public $processed = TRUE; public $unifunc = 'content_6740cb7558aae9_79447201'; public $has_nocache_code = FALSE; public $file_dependency = [...]; public $content = NULL; public $includes = [...]; public $isCache = FALSE; public $nocache_hash = NULL } } ).../smarty_internal_template.php:217
130.315223205152Smarty_Template_Resource_Base->getRenderedTemplateCode( $_template = class Smarty_Internal_Template { public $_objType = 2; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = ['SCRIPT_NAME' => class Smarty_Variable { ... }, 'defaultCharset' => class Smarty_Variable { ... }, 'baseUrl' => class Smarty_Variable { ... }, 'currentContext' => class Smarty_Variable { ... }, 'currentLocale' => class Smarty_Variable { ... }, 'currentLocaleLangDir' => class Smarty_Variable { ... }, 'applicationName' => class Smarty_Variable { ... }, 'dateFormatShort' => class Smarty_Variable { ... }, 'dateFormatLong' => class Smarty_Variable { ... }, 'datetimeFormatShort' => class Smarty_Variable { ... }, 'datetimeFormatLong' => class Smarty_Variable { ... }, 'timeFormat' => class Smarty_Variable { ... }, 'displayPageHeaderTitle' => class Smarty_Variable { ... }, 'displayPageHeaderLogo' => class Smarty_Variable { ... }, 'displayPageHeaderLogoAltText' => class Smarty_Variable { ... }, 'activeTheme' => class Smarty_Variable { ... }, 'requestedPage' => class Smarty_Variable { ... }, 'requestedOp' => class Smarty_Variable { ... }, 'fbvStyles' => class Smarty_Variable { ... }, 'isUserLoggedIn' => class Smarty_Variable { ... }, 'isUserLoggedInAs' => class Smarty_Variable { ... }, 'itemsPerPage' => class Smarty_Variable { ... }, 'numPageLinks' => class Smarty_Variable { ... }, 'siteTitle' => class Smarty_Variable { ... }, 'hasSidebar' => class Smarty_Variable { ... }, 'brandImage' => class Smarty_Variable { ... }, 'sitePublicFilesDir' => class Smarty_Variable { ... }, 'publicFilesDir' => class Smarty_Variable { ... }, 'currentJournal' => class Smarty_Variable { ... }, 'primaryLocale' => class Smarty_Variable { ... }, 'supportedLocales' => class Smarty_Variable { ... }, 'enableAnnouncements' => class Smarty_Variable { ... }, 'disableUserReg' => class Smarty_Variable { ... }, 'pageFooter' => class Smarty_Variable { ... }, 'issue' => class Smarty_Variable { ... }, 'article' => class Smarty_Variable { ... }, 'publication' => class Smarty_Variable { ... }, 'currentPublication' => class Smarty_Variable { ... }, 'galley' => class Smarty_Variable { ... }, 'fileId' => class Smarty_Variable { ... }, 'submissionFileId' => class Smarty_Variable { ... }, 'userRoles' => class Smarty_Variable { ... }, 'firstPublication' => class Smarty_Variable { ... }, 'ccLicenseBadge' => class Smarty_Variable { ... }, 'section' => class Smarty_Variable { ... }, 'categories' => class Smarty_Variable { ... }, 'primaryGalleys' => class Smarty_Variable { ... }, 'supplementaryGalleys' => class Smarty_Variable { ... }, 'userGroupsById' => class Smarty_Variable { ... }, 'parsedCitations' => class Smarty_Variable { ... }, 'licenseTerms' => class Smarty_Variable { ... }, 'licenseUrl' => class Smarty_Variable { ... }, 'copyrightHolder' => class Smarty_Variable { ... }, 'copyrightYear' => class Smarty_Variable { ... }, 'pubIdPlugins' => class Smarty_Variable { ... }, 'keywords' => class Smarty_Variable { ... }, 'hasAccess' => class Smarty_Variable { ... }, 'citation' => class Smarty_Variable { ... }, 'citationArgs' => class Smarty_Variable { ... }, 'citationArgsJson' => class Smarty_Variable { ... }, 'citationStyles' => class Smarty_Variable { ... }, 'citationDownloads' => class Smarty_Variable { ... }, 'state' => class Smarty_Variable { ... }]; public $parent = class APP\template\TemplateManager { public $_objType = 1; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = [...]; public $parent = NULL; public $config_vars = [...]; public $ext = class Smarty_Internal_Extension_Handler { ... }; public $cache_id = NULL; public $compile_id = NULL; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = [...]; public $_cache = [...]; public $auto_literal = TRUE; public $error_unassigned = FALSE; public $use_include_path = FALSE; public $_templateDirNormalized = TRUE; public $_joined_template_dir = '/var/www/html/templates/#/var/www/html/plugins/themes/default/templates/'; public $_configDirNormalized = FALSE; public $_joined_config_dir = NULL; public $default_template_handler_func = NULL; public $default_config_handler_func = NULL; public $default_plugin_handler_func = NULL; public $_compileDirNormalized = TRUE; public $_pluginsDirNormalized = FALSE; public $_cacheDirNormalized = FALSE; public $force_compile = FALSE; public $use_sub_dirs = FALSE; public $allow_ambiguous_resources = FALSE; public $merge_compiled_includes = FALSE; public $extends_recursion = TRUE; public $force_cache = FALSE; public $left_delimiter = '{'; public $right_delimiter = '}'; public $literals = [...]; public $security_class = 'Smarty_Security'; public $security_policy = NULL; public $allow_php_templates = FALSE; public $debugging = FALSE; public $debugging_ctrl = 'NONE'; public $smarty_debug_id = 'SMARTY_DEBUG'; public $debug_tpl = NULL; public $error_reporting = 32757; public $config_overwrite = TRUE; public $config_booleanize = TRUE; public $config_read_hidden = FALSE; public $compile_locking = TRUE; public $cache_locking = FALSE; public $locking_timeout = 10; public $default_resource_type = 'app'; public $caching_type = 'file'; public $default_config_type = 'file'; public $cache_modified_check = FALSE; public $registered_plugins = [...]; public $registered_objects = [...]; public $registered_classes = [...]; public $registered_filters = [...]; public $registered_resources = [...]; public $registered_cache_resources = [...]; public $autoload_filters = [...]; public $default_modifiers = [...]; public $escape_html = FALSE; public $start_time = 1732555447.2556; public $_current_file = NULL; public $_parserdebug = FALSE; public $_debug = NULL; protected $template_dir = [...]; protected $_processedTemplateDir = [...]; protected $config_dir = '/var/www/html/cache/t_config'; protected $_processedConfigDir = [...]; protected $compile_dir = '/var/www/html/cache/t_compile/'; protected $plugins_dir = [...]; protected $cache_dir = '/var/www/html/cache/t_cache'; protected $obsoleteProperties = [...]; protected $accessMap = [...]; private ${Smarty}isMutingUndefinedOrNullWarnings = FALSE; private ${PKP\template\PKPTemplateManager}_styleSheets = [...]; private ${PKP\template\PKPTemplateManager}_javaScripts = [...]; private ${PKP\template\PKPTemplateManager}_htmlHeaders = [...]; private ${PKP\template\PKPTemplateManager}_constants = [...]; private ${PKP\template\PKPTemplateManager}_localeKeys = [...]; protected $_state = [...]; private ${PKP\template\PKPTemplateManager}_cacheability = 'no-store'; private ${PKP\template\PKPTemplateManager}_fbv = class PKP\form\FormBuilderVocabulary { ... }; private ${PKP\template\PKPTemplateManager}_request = class APP\core\Request { ... }; private array ${PKP\template\PKPTemplateManager}headers = [...]; private bool ${PKP\template\PKPTemplateManager}isBackendPage = FALSE }; public $config_vars = []; public $ext = class Smarty_Internal_Extension_Handler { public $objType = 2; private $_property_info = [...]; private $resolvedProperties = [...]; public $getTemplateVars = class Smarty_Internal_Method_GetTemplateVars { ... } }; public $cache_id = NULL; public $compile_id = '42362804174f266c598cdb32c3208fc745b92101'; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = []; public $_cache = []; public $smarty = class APP\template\TemplateManager { public $_objType = 1; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = [...]; public $parent = NULL; public $config_vars = [...]; public $ext = class Smarty_Internal_Extension_Handler { ... }; public $cache_id = NULL; public $compile_id = NULL; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = [...]; public $_cache = [...]; public $auto_literal = TRUE; public $error_unassigned = FALSE; public $use_include_path = FALSE; public $_templateDirNormalized = TRUE; public $_joined_template_dir = '/var/www/html/templates/#/var/www/html/plugins/themes/default/templates/'; public $_configDirNormalized = FALSE; public $_joined_config_dir = NULL; public $default_template_handler_func = NULL; public $default_config_handler_func = NULL; public $default_plugin_handler_func = NULL; public $_compileDirNormalized = TRUE; public $_pluginsDirNormalized = FALSE; public $_cacheDirNormalized = FALSE; public $force_compile = FALSE; public $use_sub_dirs = FALSE; public $allow_ambiguous_resources = FALSE; public $merge_compiled_includes = FALSE; public $extends_recursion = TRUE; public $force_cache = FALSE; public $left_delimiter = '{'; public $right_delimiter = '}'; public $literals = [...]; public $security_class = 'Smarty_Security'; public $security_policy = NULL; public $allow_php_templates = FALSE; public $debugging = FALSE; public $debugging_ctrl = 'NONE'; public $smarty_debug_id = 'SMARTY_DEBUG'; public $debug_tpl = NULL; public $error_reporting = 32757; public $config_overwrite = TRUE; public $config_booleanize = TRUE; public $config_read_hidden = FALSE; public $compile_locking = TRUE; public $cache_locking = FALSE; public $locking_timeout = 10; public $default_resource_type = 'app'; public $caching_type = 'file'; public $default_config_type = 'file'; public $cache_modified_check = FALSE; public $registered_plugins = [...]; public $registered_objects = [...]; public $registered_classes = [...]; public $registered_filters = [...]; public $registered_resources = [...]; public $registered_cache_resources = [...]; public $autoload_filters = [...]; public $default_modifiers = [...]; public $escape_html = FALSE; public $start_time = 1732555447.2556; public $_current_file = NULL; public $_parserdebug = FALSE; public $_debug = NULL; protected $template_dir = [...]; protected $_processedTemplateDir = [...]; protected $config_dir = '/var/www/html/cache/t_config'; protected $_processedConfigDir = [...]; protected $compile_dir = '/var/www/html/cache/t_compile/'; protected $plugins_dir = [...]; protected $cache_dir = '/var/www/html/cache/t_cache'; protected $obsoleteProperties = [...]; protected $accessMap = [...]; private ${Smarty}isMutingUndefinedOrNullWarnings = FALSE; private ${PKP\template\PKPTemplateManager}_styleSheets = [...]; private ${PKP\template\PKPTemplateManager}_javaScripts = [...]; private ${PKP\template\PKPTemplateManager}_htmlHeaders = [...]; private ${PKP\template\PKPTemplateManager}_constants = [...]; private ${PKP\template\PKPTemplateManager}_localeKeys = [...]; protected $_state = [...]; private ${PKP\template\PKPTemplateManager}_cacheability = 'no-store'; private ${PKP\template\PKPTemplateManager}_fbv = class PKP\form\FormBuilderVocabulary { ... }; private ${PKP\template\PKPTemplateManager}_request = class APP\core\Request { ... }; private array ${PKP\template\PKPTemplateManager}headers = [...]; private bool ${PKP\template\PKPTemplateManager}isBackendPage = FALSE }; public $source = class Smarty_Template_Source { public $uid = '1c372c95cd85572e0fbc9a53d0323a0b229cfc78'; public $resource = 'frontend/pages/article.tpl'; public $type = 'app'; public $name = 'frontend/pages/article.tpl'; public $filepath = 'app:frontendpagesarticle.tpl'; public $timestamp = 1724439197; public $exists = TRUE; public $basename = NULL; public $components = NULL; public $handler = class PKP\template\PKPTemplateResource { ... }; public $smarty = class APP\template\TemplateManager { ... }; public $isConfig = FALSE; public $content = NULL; public $compiler_class = 'Smarty_Internal_SmartyTemplateCompiler'; public $template_lexer_class = 'Smarty_Internal_Templatelexer'; public $template_parser_class = 'Smarty_Internal_Templateparser' }; public $inheritance = NULL; public $template_resource = 'frontend/pages/article.tpl'; public $mustCompile = FALSE; public $templateId = '/var/www/html/templates/#/var/www/html/plugins/themes/default/templates/#app:frontend/pages/article.tpl##42362804174f266c598cdb32c3208fc745b92101#0'; public $scope = 0; public $isRenderingCache = FALSE; public $startRenderCallbacks = []; public $endRenderCallbacks = []; public $compiled = class Smarty_Template_Compiled { public $filepath = '/var/www/html/cache/t_compile/42362804174f266c598cdb32c3208fc745b92101^1c372c95cd85572e0fbc9a53d0323a0b229cfc78_0.app.frontendpagesarticle.tpl.php'; public $timestamp = 1732299637; public $exists = TRUE; public $compile_id = NULL; public $processed = TRUE; public $unifunc = 'content_6740cb7558aae9_79447201'; public $has_nocache_code = FALSE; public $file_dependency = [...]; public $content = NULL; public $includes = [...]; public $isCache = FALSE; public $nocache_hash = NULL } }, $unifunc = ??? ).../smarty_template_compiled.php:114
140.315223205152content_6740cb7558aae9_79447201( $_smarty_tpl = class Smarty_Internal_Template { public $_objType = 2; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = ['SCRIPT_NAME' => class Smarty_Variable { ... }, 'defaultCharset' => class Smarty_Variable { ... }, 'baseUrl' => class Smarty_Variable { ... }, 'currentContext' => class Smarty_Variable { ... }, 'currentLocale' => class Smarty_Variable { ... }, 'currentLocaleLangDir' => class Smarty_Variable { ... }, 'applicationName' => class Smarty_Variable { ... }, 'dateFormatShort' => class Smarty_Variable { ... }, 'dateFormatLong' => class Smarty_Variable { ... }, 'datetimeFormatShort' => class Smarty_Variable { ... }, 'datetimeFormatLong' => class Smarty_Variable { ... }, 'timeFormat' => class Smarty_Variable { ... }, 'displayPageHeaderTitle' => class Smarty_Variable { ... }, 'displayPageHeaderLogo' => class Smarty_Variable { ... }, 'displayPageHeaderLogoAltText' => class Smarty_Variable { ... }, 'activeTheme' => class Smarty_Variable { ... }, 'requestedPage' => class Smarty_Variable { ... }, 'requestedOp' => class Smarty_Variable { ... }, 'fbvStyles' => class Smarty_Variable { ... }, 'isUserLoggedIn' => class Smarty_Variable { ... }, 'isUserLoggedInAs' => class Smarty_Variable { ... }, 'itemsPerPage' => class Smarty_Variable { ... }, 'numPageLinks' => class Smarty_Variable { ... }, 'siteTitle' => class Smarty_Variable { ... }, 'hasSidebar' => class Smarty_Variable { ... }, 'brandImage' => class Smarty_Variable { ... }, 'sitePublicFilesDir' => class Smarty_Variable { ... }, 'publicFilesDir' => class Smarty_Variable { ... }, 'currentJournal' => class Smarty_Variable { ... }, 'primaryLocale' => class Smarty_Variable { ... }, 'supportedLocales' => class Smarty_Variable { ... }, 'enableAnnouncements' => class Smarty_Variable { ... }, 'disableUserReg' => class Smarty_Variable { ... }, 'pageFooter' => class Smarty_Variable { ... }, 'issue' => class Smarty_Variable { ... }, 'article' => class Smarty_Variable { ... }, 'publication' => class Smarty_Variable { ... }, 'currentPublication' => class Smarty_Variable { ... }, 'galley' => class Smarty_Variable { ... }, 'fileId' => class Smarty_Variable { ... }, 'submissionFileId' => class Smarty_Variable { ... }, 'userRoles' => class Smarty_Variable { ... }, 'firstPublication' => class Smarty_Variable { ... }, 'ccLicenseBadge' => class Smarty_Variable { ... }, 'section' => class Smarty_Variable { ... }, 'categories' => class Smarty_Variable { ... }, 'primaryGalleys' => class Smarty_Variable { ... }, 'supplementaryGalleys' => class Smarty_Variable { ... }, 'userGroupsById' => class Smarty_Variable { ... }, 'parsedCitations' => class Smarty_Variable { ... }, 'licenseTerms' => class Smarty_Variable { ... }, 'licenseUrl' => class Smarty_Variable { ... }, 'copyrightHolder' => class Smarty_Variable { ... }, 'copyrightYear' => class Smarty_Variable { ... }, 'pubIdPlugins' => class Smarty_Variable { ... }, 'keywords' => class Smarty_Variable { ... }, 'hasAccess' => class Smarty_Variable { ... }, 'citation' => class Smarty_Variable { ... }, 'citationArgs' => class Smarty_Variable { ... }, 'citationArgsJson' => class Smarty_Variable { ... }, 'citationStyles' => class Smarty_Variable { ... }, 'citationDownloads' => class Smarty_Variable { ... }, 'state' => class Smarty_Variable { ... }]; public $parent = class APP\template\TemplateManager { public $_objType = 1; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = [...]; public $parent = NULL; public $config_vars = [...]; public $ext = class Smarty_Internal_Extension_Handler { ... }; public $cache_id = NULL; public $compile_id = NULL; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = [...]; public $_cache = [...]; public $auto_literal = TRUE; public $error_unassigned = FALSE; public $use_include_path = FALSE; public $_templateDirNormalized = TRUE; public $_joined_template_dir = '/var/www/html/templates/#/var/www/html/plugins/themes/default/templates/'; public $_configDirNormalized = FALSE; public $_joined_config_dir = NULL; public $default_template_handler_func = NULL; public $default_config_handler_func = NULL; public $default_plugin_handler_func = NULL; public $_compileDirNormalized = TRUE; public $_pluginsDirNormalized = FALSE; public $_cacheDirNormalized = FALSE; public $force_compile = FALSE; public $use_sub_dirs = FALSE; public $allow_ambiguous_resources = FALSE; public $merge_compiled_includes = FALSE; public $extends_recursion = TRUE; public $force_cache = FALSE; public $left_delimiter = '{'; public $right_delimiter = '}'; public $literals = [...]; public $security_class = 'Smarty_Security'; public $security_policy = NULL; public $allow_php_templates = FALSE; public $debugging = FALSE; public $debugging_ctrl = 'NONE'; public $smarty_debug_id = 'SMARTY_DEBUG'; public $debug_tpl = NULL; public $error_reporting = 32757; public $config_overwrite = TRUE; public $config_booleanize = TRUE; public $config_read_hidden = FALSE; public $compile_locking = TRUE; public $cache_locking = FALSE; public $locking_timeout = 10; public $default_resource_type = 'app'; public $caching_type = 'file'; public $default_config_type = 'file'; public $cache_modified_check = FALSE; public $registered_plugins = [...]; public $registered_objects = [...]; public $registered_classes = [...]; public $registered_filters = [...]; public $registered_resources = [...]; public $registered_cache_resources = [...]; public $autoload_filters = [...]; public $default_modifiers = [...]; public $escape_html = FALSE; public $start_time = 1732555447.2556; public $_current_file = NULL; public $_parserdebug = FALSE; public $_debug = NULL; protected $template_dir = [...]; protected $_processedTemplateDir = [...]; protected $config_dir = '/var/www/html/cache/t_config'; protected $_processedConfigDir = [...]; protected $compile_dir = '/var/www/html/cache/t_compile/'; protected $plugins_dir = [...]; protected $cache_dir = '/var/www/html/cache/t_cache'; protected $obsoleteProperties = [...]; protected $accessMap = [...]; private ${Smarty}isMutingUndefinedOrNullWarnings = FALSE; private ${PKP\template\PKPTemplateManager}_styleSheets = [...]; private ${PKP\template\PKPTemplateManager}_javaScripts = [...]; private ${PKP\template\PKPTemplateManager}_htmlHeaders = [...]; private ${PKP\template\PKPTemplateManager}_constants = [...]; private ${PKP\template\PKPTemplateManager}_localeKeys = [...]; protected $_state = [...]; private ${PKP\template\PKPTemplateManager}_cacheability = 'no-store'; private ${PKP\template\PKPTemplateManager}_fbv = class PKP\form\FormBuilderVocabulary { ... }; private ${PKP\template\PKPTemplateManager}_request = class APP\core\Request { ... }; private array ${PKP\template\PKPTemplateManager}headers = [...]; private bool ${PKP\template\PKPTemplateManager}isBackendPage = FALSE }; public $config_vars = []; public $ext = class Smarty_Internal_Extension_Handler { public $objType = 2; private $_property_info = [...]; private $resolvedProperties = [...]; public $getTemplateVars = class Smarty_Internal_Method_GetTemplateVars { ... } }; public $cache_id = NULL; public $compile_id = '42362804174f266c598cdb32c3208fc745b92101'; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = []; public $_cache = []; public $smarty = class APP\template\TemplateManager { public $_objType = 1; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = [...]; public $parent = NULL; public $config_vars = [...]; public $ext = class Smarty_Internal_Extension_Handler { ... }; public $cache_id = NULL; public $compile_id = NULL; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = [...]; public $_cache = [...]; public $auto_literal = TRUE; public $error_unassigned = FALSE; public $use_include_path = FALSE; public $_templateDirNormalized = TRUE; public $_joined_template_dir = '/var/www/html/templates/#/var/www/html/plugins/themes/default/templates/'; public $_configDirNormalized = FALSE; public $_joined_config_dir = NULL; public $default_template_handler_func = NULL; public $default_config_handler_func = NULL; public $default_plugin_handler_func = NULL; public $_compileDirNormalized = TRUE; public $_pluginsDirNormalized = FALSE; public $_cacheDirNormalized = FALSE; public $force_compile = FALSE; public $use_sub_dirs = FALSE; public $allow_ambiguous_resources = FALSE; public $merge_compiled_includes = FALSE; public $extends_recursion = TRUE; public $force_cache = FALSE; public $left_delimiter = '{'; public $right_delimiter = '}'; public $literals = [...]; public $security_class = 'Smarty_Security'; public $security_policy = NULL; public $allow_php_templates = FALSE; public $debugging = FALSE; public $debugging_ctrl = 'NONE'; public $smarty_debug_id = 'SMARTY_DEBUG'; public $debug_tpl = NULL; public $error_reporting = 32757; public $config_overwrite = TRUE; public $config_booleanize = TRUE; public $config_read_hidden = FALSE; public $compile_locking = TRUE; public $cache_locking = FALSE; public $locking_timeout = 10; public $default_resource_type = 'app'; public $caching_type = 'file'; public $default_config_type = 'file'; public $cache_modified_check = FALSE; public $registered_plugins = [...]; public $registered_objects = [...]; public $registered_classes = [...]; public $registered_filters = [...]; public $registered_resources = [...]; public $registered_cache_resources = [...]; public $autoload_filters = [...]; public $default_modifiers = [...]; public $escape_html = FALSE; public $start_time = 1732555447.2556; public $_current_file = NULL; public $_parserdebug = FALSE; public $_debug = NULL; protected $template_dir = [...]; protected $_processedTemplateDir = [...]; protected $config_dir = '/var/www/html/cache/t_config'; protected $_processedConfigDir = [...]; protected $compile_dir = '/var/www/html/cache/t_compile/'; protected $plugins_dir = [...]; protected $cache_dir = '/var/www/html/cache/t_cache'; protected $obsoleteProperties = [...]; protected $accessMap = [...]; private ${Smarty}isMutingUndefinedOrNullWarnings = FALSE; private ${PKP\template\PKPTemplateManager}_styleSheets = [...]; private ${PKP\template\PKPTemplateManager}_javaScripts = [...]; private ${PKP\template\PKPTemplateManager}_htmlHeaders = [...]; private ${PKP\template\PKPTemplateManager}_constants = [...]; private ${PKP\template\PKPTemplateManager}_localeKeys = [...]; protected $_state = [...]; private ${PKP\template\PKPTemplateManager}_cacheability = 'no-store'; private ${PKP\template\PKPTemplateManager}_fbv = class PKP\form\FormBuilderVocabulary { ... }; private ${PKP\template\PKPTemplateManager}_request = class APP\core\Request { ... }; private array ${PKP\template\PKPTemplateManager}headers = [...]; private bool ${PKP\template\PKPTemplateManager}isBackendPage = FALSE }; public $source = class Smarty_Template_Source { public $uid = '1c372c95cd85572e0fbc9a53d0323a0b229cfc78'; public $resource = 'frontend/pages/article.tpl'; public $type = 'app'; public $name = 'frontend/pages/article.tpl'; public $filepath = 'app:frontendpagesarticle.tpl'; public $timestamp = 1724439197; public $exists = TRUE; public $basename = NULL; public $components = NULL; public $handler = class PKP\template\PKPTemplateResource { ... }; public $smarty = class APP\template\TemplateManager { ... }; public $isConfig = FALSE; public $content = NULL; public $compiler_class = 'Smarty_Internal_SmartyTemplateCompiler'; public $template_lexer_class = 'Smarty_Internal_Templatelexer'; public $template_parser_class = 'Smarty_Internal_Templateparser' }; public $inheritance = NULL; public $template_resource = 'frontend/pages/article.tpl'; public $mustCompile = FALSE; public $templateId = '/var/www/html/templates/#/var/www/html/plugins/themes/default/templates/#app:frontend/pages/article.tpl##42362804174f266c598cdb32c3208fc745b92101#0'; public $scope = 0; public $isRenderingCache = FALSE; public $startRenderCallbacks = []; public $endRenderCallbacks = []; public $compiled = class Smarty_Template_Compiled { public $filepath = '/var/www/html/cache/t_compile/42362804174f266c598cdb32c3208fc745b92101^1c372c95cd85572e0fbc9a53d0323a0b229cfc78_0.app.frontendpagesarticle.tpl.php'; public $timestamp = 1732299637; public $exists = TRUE; public $compile_id = NULL; public $processed = TRUE; public $unifunc = 'content_6740cb7558aae9_79447201'; public $has_nocache_code = FALSE; public $file_dependency = [...]; public $content = NULL; public $includes = [...]; public $isCache = FALSE; public $nocache_hash = NULL } } ).../smarty_template_resource_base.php:123
150.328924815896Smarty_Internal_Template->_subTemplateRender( $template = 'app:frontend/objects/article_details.tpl', $cache_id = NULL, $compile_id = '42362804174f266c598cdb32c3208fc745b92101', $caching = 0, $cache_lifetime = 3600, $data = [], $scope = 0, $forceTplCache = FALSE, $uid = ???, $content_func = ??? ).../42362804174f266c598cdb32c3208fc745b92101^1c372c95cd85572e0fbc9a53d0323a0b229cfc78_0.app.frontendpagesarticle.tpl.php:40
160.329024818320Smarty_Internal_Template->render( $no_output_filter = ???, $display = ??? ).../smarty_internal_template.php:386
170.329024818720Smarty_Template_Compiled->render( $_template = class Smarty_Internal_Template { public $_objType = 2; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = ['SCRIPT_NAME' => class Smarty_Variable { ... }, 'defaultCharset' => class Smarty_Variable { ... }, 'baseUrl' => class Smarty_Variable { ... }, 'currentContext' => class Smarty_Variable { ... }, 'currentLocale' => class Smarty_Variable { ... }, 'currentLocaleLangDir' => class Smarty_Variable { ... }, 'applicationName' => class Smarty_Variable { ... }, 'dateFormatShort' => class Smarty_Variable { ... }, 'dateFormatLong' => class Smarty_Variable { ... }, 'datetimeFormatShort' => class Smarty_Variable { ... }, 'datetimeFormatLong' => class Smarty_Variable { ... }, 'timeFormat' => class Smarty_Variable { ... }, 'displayPageHeaderTitle' => class Smarty_Variable { ... }, 'displayPageHeaderLogo' => class Smarty_Variable { ... }, 'displayPageHeaderLogoAltText' => class Smarty_Variable { ... }, 'activeTheme' => class Smarty_Variable { ... }, 'requestedPage' => class Smarty_Variable { ... }, 'requestedOp' => class Smarty_Variable { ... }, 'fbvStyles' => class Smarty_Variable { ... }, 'isUserLoggedIn' => class Smarty_Variable { ... }, 'isUserLoggedInAs' => class Smarty_Variable { ... }, 'itemsPerPage' => class Smarty_Variable { ... }, 'numPageLinks' => class Smarty_Variable { ... }, 'siteTitle' => class Smarty_Variable { ... }, 'hasSidebar' => class Smarty_Variable { ... }, 'brandImage' => class Smarty_Variable { ... }, 'sitePublicFilesDir' => class Smarty_Variable { ... }, 'publicFilesDir' => class Smarty_Variable { ... }, 'currentJournal' => class Smarty_Variable { ... }, 'primaryLocale' => class Smarty_Variable { ... }, 'supportedLocales' => class Smarty_Variable { ... }, 'enableAnnouncements' => class Smarty_Variable { ... }, 'disableUserReg' => class Smarty_Variable { ... }, 'pageFooter' => class Smarty_Variable { ... }, 'issue' => class Smarty_Variable { ... }, 'article' => class Smarty_Variable { ... }, 'publication' => class Smarty_Variable { ... }, 'currentPublication' => class Smarty_Variable { ... }, 'galley' => class Smarty_Variable { ... }, 'fileId' => class Smarty_Variable { ... }, 'submissionFileId' => class Smarty_Variable { ... }, 'userRoles' => class Smarty_Variable { ... }, 'firstPublication' => class Smarty_Variable { ... }, 'ccLicenseBadge' => class Smarty_Variable { ... }, 'section' => class Smarty_Variable { ... }, 'categories' => class Smarty_Variable { ... }, 'primaryGalleys' => class Smarty_Variable { ... }, 'supplementaryGalleys' => class Smarty_Variable { ... }, 'userGroupsById' => class Smarty_Variable { ... }, 'parsedCitations' => class Smarty_Variable { ... }, 'licenseTerms' => class Smarty_Variable { ... }, 'licenseUrl' => class Smarty_Variable { ... }, 'copyrightHolder' => class Smarty_Variable { ... }, 'copyrightYear' => class Smarty_Variable { ... }, 'pubIdPlugins' => class Smarty_Variable { ... }, 'keywords' => class Smarty_Variable { ... }, 'hasAccess' => class Smarty_Variable { ... }, 'citation' => class Smarty_Variable { ... }, 'citationArgs' => class Smarty_Variable { ... }, 'citationArgsJson' => class Smarty_Variable { ... }, 'citationStyles' => class Smarty_Variable { ... }, 'citationDownloads' => class Smarty_Variable { ... }, 'state' => class Smarty_Variable { ... }, 'heading' => class Smarty_Variable { ... }, 'author' => class Smarty_Variable { ... }, 'authorUserGroup' => class Smarty_Variable { ... }, 'doiObject' => class Smarty_Variable { ... }, 'doiUrl' => class Smarty_Variable { ... }, 'translatedDOI' => class Smarty_Variable { ... }, 'translatedKeywords' => class Smarty_Variable { ... }, 'keyword' => class Smarty_Variable { ... }, '__smarty_foreach_keywords' => class Smarty_Variable { ... }, 'hasBiographies' => class Smarty_Variable { ... }, 'authorName' => class Smarty_Variable { ... }, 'authorAffiliation' => class Smarty_Variable { ... }, 'pubIdPlugin' => class Smarty_Variable { ... }, 'pubId' => class Smarty_Variable { ... }, 'addThisProfileId' => class Smarty_Variable { ... }, 'addThisUsername' => class Smarty_Variable { ... }, 'addThisPassword' => class Smarty_Variable { ... }, 'addThisDisplayStyle' => class Smarty_Variable { ... }]; public $parent = class Smarty_Internal_Template { public $_objType = 2; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = [...]; public $parent = class APP\template\TemplateManager { ... }; public $config_vars = [...]; public $ext = class Smarty_Internal_Extension_Handler { ... }; public $cache_id = NULL; public $compile_id = '42362804174f266c598cdb32c3208fc745b92101'; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = [...]; public $_cache = [...]; public $smarty = class APP\template\TemplateManager { ... }; public $source = class Smarty_Template_Source { ... }; public $inheritance = NULL; public $template_resource = 'frontend/pages/article.tpl'; public $mustCompile = FALSE; public $templateId = '/var/www/html/templates/#/var/www/html/plugins/themes/default/templates/#app:frontend/pages/article.tpl##42362804174f266c598cdb32c3208fc745b92101#0'; public $scope = 0; public $isRenderingCache = FALSE; public $startRenderCallbacks = [...]; public $endRenderCallbacks = [...]; public $compiled = class Smarty_Template_Compiled { ... } }; public $config_vars = []; public $ext = class Smarty_Internal_Extension_Handler { public $objType = 2; private $_property_info = [...]; private $resolvedProperties = [...]; public $getTemplateVars = class Smarty_Internal_Method_GetTemplateVars { ... } }; public $cache_id = NULL; public $compile_id = '42362804174f266c598cdb32c3208fc745b92101'; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = []; public $_cache = []; public $smarty = class APP\template\TemplateManager { public $_objType = 1; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = [...]; public $parent = NULL; public $config_vars = [...]; public $ext = class Smarty_Internal_Extension_Handler { ... }; public $cache_id = NULL; public $compile_id = NULL; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = [...]; public $_cache = [...]; public $auto_literal = TRUE; public $error_unassigned = FALSE; public $use_include_path = FALSE; public $_templateDirNormalized = TRUE; public $_joined_template_dir = '/var/www/html/templates/#/var/www/html/plugins/themes/default/templates/'; public $_configDirNormalized = FALSE; public $_joined_config_dir = NULL; public $default_template_handler_func = NULL; public $default_config_handler_func = NULL; public $default_plugin_handler_func = NULL; public $_compileDirNormalized = TRUE; public $_pluginsDirNormalized = FALSE; public $_cacheDirNormalized = FALSE; public $force_compile = FALSE; public $use_sub_dirs = FALSE; public $allow_ambiguous_resources = FALSE; public $merge_compiled_includes = FALSE; public $extends_recursion = TRUE; public $force_cache = FALSE; public $left_delimiter = '{'; public $right_delimiter = '}'; public $literals = [...]; public $security_class = 'Smarty_Security'; public $security_policy = NULL; public $allow_php_templates = FALSE; public $debugging = FALSE; public $debugging_ctrl = 'NONE'; public $smarty_debug_id = 'SMARTY_DEBUG'; public $debug_tpl = NULL; public $error_reporting = 32757; public $config_overwrite = TRUE; public $config_booleanize = TRUE; public $config_read_hidden = FALSE; public $compile_locking = TRUE; public $cache_locking = FALSE; public $locking_timeout = 10; public $default_resource_type = 'app'; public $caching_type = 'file'; public $default_config_type = 'file'; public $cache_modified_check = FALSE; public $registered_plugins = [...]; public $registered_objects = [...]; public $registered_classes = [...]; public $registered_filters = [...]; public $registered_resources = [...]; public $registered_cache_resources = [...]; public $autoload_filters = [...]; public $default_modifiers = [...]; public $escape_html = FALSE; public $start_time = 1732555447.2556; public $_current_file = NULL; public $_parserdebug = FALSE; public $_debug = NULL; protected $template_dir = [...]; protected $_processedTemplateDir = [...]; protected $config_dir = '/var/www/html/cache/t_config'; protected $_processedConfigDir = [...]; protected $compile_dir = '/var/www/html/cache/t_compile/'; protected $plugins_dir = [...]; protected $cache_dir = '/var/www/html/cache/t_cache'; protected $obsoleteProperties = [...]; protected $accessMap = [...]; private ${Smarty}isMutingUndefinedOrNullWarnings = FALSE; private ${PKP\template\PKPTemplateManager}_styleSheets = [...]; private ${PKP\template\PKPTemplateManager}_javaScripts = [...]; private ${PKP\template\PKPTemplateManager}_htmlHeaders = [...]; private ${PKP\template\PKPTemplateManager}_constants = [...]; private ${PKP\template\PKPTemplateManager}_localeKeys = [...]; protected $_state = [...]; private ${PKP\template\PKPTemplateManager}_cacheability = 'no-store'; private ${PKP\template\PKPTemplateManager}_fbv = class PKP\form\FormBuilderVocabulary { ... }; private ${PKP\template\PKPTemplateManager}_request = class APP\core\Request { ... }; private array ${PKP\template\PKPTemplateManager}headers = [...]; private bool ${PKP\template\PKPTemplateManager}isBackendPage = FALSE }; public $source = class Smarty_Template_Source { public $uid = 'addd65021fadf964339ab08cd1aa93ba59b14e9c'; public $resource = 'app:frontend/objects/article_details.tpl'; public $type = 'app'; public $name = 'frontend/objects/article_details.tpl'; public $filepath = 'app:frontendobjectsarticle_details.tpl'; public $timestamp = 1724439197; public $exists = TRUE; public $basename = NULL; public $components = NULL; public $handler = class PKP\template\PKPTemplateResource { ... }; public $smarty = class APP\template\TemplateManager { ... }; public $isConfig = FALSE; public $content = NULL; public $compiler_class = 'Smarty_Internal_SmartyTemplateCompiler'; public $template_lexer_class = 'Smarty_Internal_Templatelexer'; public $template_parser_class = 'Smarty_Internal_Templateparser' }; public $inheritance = NULL; public $template_resource = 'app:frontend/objects/article_details.tpl'; public $mustCompile = FALSE; public $templateId = '36060c7c43ad1691e04870da0cec54c0d1263666'; public $scope = 0; public $isRenderingCache = FALSE; public $startRenderCallbacks = []; public $endRenderCallbacks = []; public $compiled = class Smarty_Template_Compiled { public $filepath = '/var/www/html/cache/t_compile/42362804174f266c598cdb32c3208fc745b92101^addd65021fadf964339ab08cd1aa93ba59b14e9c_0.app.frontendobjectsarticle_details.tpl.php'; public $timestamp = 1732299637; public $exists = TRUE; public $compile_id = NULL; public $processed = TRUE; public $unifunc = 'content_6740cb7578e617_99827455'; public $has_nocache_code = FALSE; public $file_dependency = [...]; public $content = NULL; public $includes = [...]; public $isCache = FALSE; public $nocache_hash = NULL } } ).../smarty_internal_template.php:217
180.329624969584Smarty_Template_Resource_Base->getRenderedTemplateCode( $_template = class Smarty_Internal_Template { public $_objType = 2; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = ['SCRIPT_NAME' => class Smarty_Variable { ... }, 'defaultCharset' => class Smarty_Variable { ... }, 'baseUrl' => class Smarty_Variable { ... }, 'currentContext' => class Smarty_Variable { ... }, 'currentLocale' => class Smarty_Variable { ... }, 'currentLocaleLangDir' => class Smarty_Variable { ... }, 'applicationName' => class Smarty_Variable { ... }, 'dateFormatShort' => class Smarty_Variable { ... }, 'dateFormatLong' => class Smarty_Variable { ... }, 'datetimeFormatShort' => class Smarty_Variable { ... }, 'datetimeFormatLong' => class Smarty_Variable { ... }, 'timeFormat' => class Smarty_Variable { ... }, 'displayPageHeaderTitle' => class Smarty_Variable { ... }, 'displayPageHeaderLogo' => class Smarty_Variable { ... }, 'displayPageHeaderLogoAltText' => class Smarty_Variable { ... }, 'activeTheme' => class Smarty_Variable { ... }, 'requestedPage' => class Smarty_Variable { ... }, 'requestedOp' => class Smarty_Variable { ... }, 'fbvStyles' => class Smarty_Variable { ... }, 'isUserLoggedIn' => class Smarty_Variable { ... }, 'isUserLoggedInAs' => class Smarty_Variable { ... }, 'itemsPerPage' => class Smarty_Variable { ... }, 'numPageLinks' => class Smarty_Variable { ... }, 'siteTitle' => class Smarty_Variable { ... }, 'hasSidebar' => class Smarty_Variable { ... }, 'brandImage' => class Smarty_Variable { ... }, 'sitePublicFilesDir' => class Smarty_Variable { ... }, 'publicFilesDir' => class Smarty_Variable { ... }, 'currentJournal' => class Smarty_Variable { ... }, 'primaryLocale' => class Smarty_Variable { ... }, 'supportedLocales' => class Smarty_Variable { ... }, 'enableAnnouncements' => class Smarty_Variable { ... }, 'disableUserReg' => class Smarty_Variable { ... }, 'pageFooter' => class Smarty_Variable { ... }, 'issue' => class Smarty_Variable { ... }, 'article' => class Smarty_Variable { ... }, 'publication' => class Smarty_Variable { ... }, 'currentPublication' => class Smarty_Variable { ... }, 'galley' => class Smarty_Variable { ... }, 'fileId' => class Smarty_Variable { ... }, 'submissionFileId' => class Smarty_Variable { ... }, 'userRoles' => class Smarty_Variable { ... }, 'firstPublication' => class Smarty_Variable { ... }, 'ccLicenseBadge' => class Smarty_Variable { ... }, 'section' => class Smarty_Variable { ... }, 'categories' => class Smarty_Variable { ... }, 'primaryGalleys' => class Smarty_Variable { ... }, 'supplementaryGalleys' => class Smarty_Variable { ... }, 'userGroupsById' => class Smarty_Variable { ... }, 'parsedCitations' => class Smarty_Variable { ... }, 'licenseTerms' => class Smarty_Variable { ... }, 'licenseUrl' => class Smarty_Variable { ... }, 'copyrightHolder' => class Smarty_Variable { ... }, 'copyrightYear' => class Smarty_Variable { ... }, 'pubIdPlugins' => class Smarty_Variable { ... }, 'keywords' => class Smarty_Variable { ... }, 'hasAccess' => class Smarty_Variable { ... }, 'citation' => class Smarty_Variable { ... }, 'citationArgs' => class Smarty_Variable { ... }, 'citationArgsJson' => class Smarty_Variable { ... }, 'citationStyles' => class Smarty_Variable { ... }, 'citationDownloads' => class Smarty_Variable { ... }, 'state' => class Smarty_Variable { ... }, 'heading' => class Smarty_Variable { ... }, 'author' => class Smarty_Variable { ... }, 'authorUserGroup' => class Smarty_Variable { ... }, 'doiObject' => class Smarty_Variable { ... }, 'doiUrl' => class Smarty_Variable { ... }, 'translatedDOI' => class Smarty_Variable { ... }, 'translatedKeywords' => class Smarty_Variable { ... }, 'keyword' => class Smarty_Variable { ... }, '__smarty_foreach_keywords' => class Smarty_Variable { ... }, 'hasBiographies' => class Smarty_Variable { ... }, 'authorName' => class Smarty_Variable { ... }, 'authorAffiliation' => class Smarty_Variable { ... }, 'pubIdPlugin' => class Smarty_Variable { ... }, 'pubId' => class Smarty_Variable { ... }, 'addThisProfileId' => class Smarty_Variable { ... }, 'addThisUsername' => class Smarty_Variable { ... }, 'addThisPassword' => class Smarty_Variable { ... }, 'addThisDisplayStyle' => class Smarty_Variable { ... }]; public $parent = class Smarty_Internal_Template { public $_objType = 2; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = [...]; public $parent = class APP\template\TemplateManager { ... }; public $config_vars = [...]; public $ext = class Smarty_Internal_Extension_Handler { ... }; public $cache_id = NULL; public $compile_id = '42362804174f266c598cdb32c3208fc745b92101'; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = [...]; public $_cache = [...]; public $smarty = class APP\template\TemplateManager { ... }; public $source = class Smarty_Template_Source { ... }; public $inheritance = NULL; public $template_resource = 'frontend/pages/article.tpl'; public $mustCompile = FALSE; public $templateId = '/var/www/html/templates/#/var/www/html/plugins/themes/default/templates/#app:frontend/pages/article.tpl##42362804174f266c598cdb32c3208fc745b92101#0'; public $scope = 0; public $isRenderingCache = FALSE; public $startRenderCallbacks = [...]; public $endRenderCallbacks = [...]; public $compiled = class Smarty_Template_Compiled { ... } }; public $config_vars = []; public $ext = class Smarty_Internal_Extension_Handler { public $objType = 2; private $_property_info = [...]; private $resolvedProperties = [...]; public $getTemplateVars = class Smarty_Internal_Method_GetTemplateVars { ... } }; public $cache_id = NULL; public $compile_id = '42362804174f266c598cdb32c3208fc745b92101'; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = []; public $_cache = []; public $smarty = class APP\template\TemplateManager { public $_objType = 1; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = [...]; public $parent = NULL; public $config_vars = [...]; public $ext = class Smarty_Internal_Extension_Handler { ... }; public $cache_id = NULL; public $compile_id = NULL; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = [...]; public $_cache = [...]; public $auto_literal = TRUE; public $error_unassigned = FALSE; public $use_include_path = FALSE; public $_templateDirNormalized = TRUE; public $_joined_template_dir = '/var/www/html/templates/#/var/www/html/plugins/themes/default/templates/'; public $_configDirNormalized = FALSE; public $_joined_config_dir = NULL; public $default_template_handler_func = NULL; public $default_config_handler_func = NULL; public $default_plugin_handler_func = NULL; public $_compileDirNormalized = TRUE; public $_pluginsDirNormalized = FALSE; public $_cacheDirNormalized = FALSE; public $force_compile = FALSE; public $use_sub_dirs = FALSE; public $allow_ambiguous_resources = FALSE; public $merge_compiled_includes = FALSE; public $extends_recursion = TRUE; public $force_cache = FALSE; public $left_delimiter = '{'; public $right_delimiter = '}'; public $literals = [...]; public $security_class = 'Smarty_Security'; public $security_policy = NULL; public $allow_php_templates = FALSE; public $debugging = FALSE; public $debugging_ctrl = 'NONE'; public $smarty_debug_id = 'SMARTY_DEBUG'; public $debug_tpl = NULL; public $error_reporting = 32757; public $config_overwrite = TRUE; public $config_booleanize = TRUE; public $config_read_hidden = FALSE; public $compile_locking = TRUE; public $cache_locking = FALSE; public $locking_timeout = 10; public $default_resource_type = 'app'; public $caching_type = 'file'; public $default_config_type = 'file'; public $cache_modified_check = FALSE; public $registered_plugins = [...]; public $registered_objects = [...]; public $registered_classes = [...]; public $registered_filters = [...]; public $registered_resources = [...]; public $registered_cache_resources = [...]; public $autoload_filters = [...]; public $default_modifiers = [...]; public $escape_html = FALSE; public $start_time = 1732555447.2556; public $_current_file = NULL; public $_parserdebug = FALSE; public $_debug = NULL; protected $template_dir = [...]; protected $_processedTemplateDir = [...]; protected $config_dir = '/var/www/html/cache/t_config'; protected $_processedConfigDir = [...]; protected $compile_dir = '/var/www/html/cache/t_compile/'; protected $plugins_dir = [...]; protected $cache_dir = '/var/www/html/cache/t_cache'; protected $obsoleteProperties = [...]; protected $accessMap = [...]; private ${Smarty}isMutingUndefinedOrNullWarnings = FALSE; private ${PKP\template\PKPTemplateManager}_styleSheets = [...]; private ${PKP\template\PKPTemplateManager}_javaScripts = [...]; private ${PKP\template\PKPTemplateManager}_htmlHeaders = [...]; private ${PKP\template\PKPTemplateManager}_constants = [...]; private ${PKP\template\PKPTemplateManager}_localeKeys = [...]; protected $_state = [...]; private ${PKP\template\PKPTemplateManager}_cacheability = 'no-store'; private ${PKP\template\PKPTemplateManager}_fbv = class PKP\form\FormBuilderVocabulary { ... }; private ${PKP\template\PKPTemplateManager}_request = class APP\core\Request { ... }; private array ${PKP\template\PKPTemplateManager}headers = [...]; private bool ${PKP\template\PKPTemplateManager}isBackendPage = FALSE }; public $source = class Smarty_Template_Source { public $uid = 'addd65021fadf964339ab08cd1aa93ba59b14e9c'; public $resource = 'app:frontend/objects/article_details.tpl'; public $type = 'app'; public $name = 'frontend/objects/article_details.tpl'; public $filepath = 'app:frontendobjectsarticle_details.tpl'; public $timestamp = 1724439197; public $exists = TRUE; public $basename = NULL; public $components = NULL; public $handler = class PKP\template\PKPTemplateResource { ... }; public $smarty = class APP\template\TemplateManager { ... }; public $isConfig = FALSE; public $content = NULL; public $compiler_class = 'Smarty_Internal_SmartyTemplateCompiler'; public $template_lexer_class = 'Smarty_Internal_Templatelexer'; public $template_parser_class = 'Smarty_Internal_Templateparser' }; public $inheritance = NULL; public $template_resource = 'app:frontend/objects/article_details.tpl'; public $mustCompile = FALSE; public $templateId = '36060c7c43ad1691e04870da0cec54c0d1263666'; public $scope = 0; public $isRenderingCache = FALSE; public $startRenderCallbacks = []; public $endRenderCallbacks = []; public $compiled = class Smarty_Template_Compiled { public $filepath = '/var/www/html/cache/t_compile/42362804174f266c598cdb32c3208fc745b92101^addd65021fadf964339ab08cd1aa93ba59b14e9c_0.app.frontendobjectsarticle_details.tpl.php'; public $timestamp = 1732299637; public $exists = TRUE; public $compile_id = NULL; public $processed = TRUE; public $unifunc = 'content_6740cb7578e617_99827455'; public $has_nocache_code = FALSE; public $file_dependency = [...]; public $content = NULL; public $includes = [...]; public $isCache = FALSE; public $nocache_hash = NULL } }, $unifunc = ??? ).../smarty_template_compiled.php:114
190.329724969584content_6740cb7578e617_99827455( $_smarty_tpl = class Smarty_Internal_Template { public $_objType = 2; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = ['SCRIPT_NAME' => class Smarty_Variable { ... }, 'defaultCharset' => class Smarty_Variable { ... }, 'baseUrl' => class Smarty_Variable { ... }, 'currentContext' => class Smarty_Variable { ... }, 'currentLocale' => class Smarty_Variable { ... }, 'currentLocaleLangDir' => class Smarty_Variable { ... }, 'applicationName' => class Smarty_Variable { ... }, 'dateFormatShort' => class Smarty_Variable { ... }, 'dateFormatLong' => class Smarty_Variable { ... }, 'datetimeFormatShort' => class Smarty_Variable { ... }, 'datetimeFormatLong' => class Smarty_Variable { ... }, 'timeFormat' => class Smarty_Variable { ... }, 'displayPageHeaderTitle' => class Smarty_Variable { ... }, 'displayPageHeaderLogo' => class Smarty_Variable { ... }, 'displayPageHeaderLogoAltText' => class Smarty_Variable { ... }, 'activeTheme' => class Smarty_Variable { ... }, 'requestedPage' => class Smarty_Variable { ... }, 'requestedOp' => class Smarty_Variable { ... }, 'fbvStyles' => class Smarty_Variable { ... }, 'isUserLoggedIn' => class Smarty_Variable { ... }, 'isUserLoggedInAs' => class Smarty_Variable { ... }, 'itemsPerPage' => class Smarty_Variable { ... }, 'numPageLinks' => class Smarty_Variable { ... }, 'siteTitle' => class Smarty_Variable { ... }, 'hasSidebar' => class Smarty_Variable { ... }, 'brandImage' => class Smarty_Variable { ... }, 'sitePublicFilesDir' => class Smarty_Variable { ... }, 'publicFilesDir' => class Smarty_Variable { ... }, 'currentJournal' => class Smarty_Variable { ... }, 'primaryLocale' => class Smarty_Variable { ... }, 'supportedLocales' => class Smarty_Variable { ... }, 'enableAnnouncements' => class Smarty_Variable { ... }, 'disableUserReg' => class Smarty_Variable { ... }, 'pageFooter' => class Smarty_Variable { ... }, 'issue' => class Smarty_Variable { ... }, 'article' => class Smarty_Variable { ... }, 'publication' => class Smarty_Variable { ... }, 'currentPublication' => class Smarty_Variable { ... }, 'galley' => class Smarty_Variable { ... }, 'fileId' => class Smarty_Variable { ... }, 'submissionFileId' => class Smarty_Variable { ... }, 'userRoles' => class Smarty_Variable { ... }, 'firstPublication' => class Smarty_Variable { ... }, 'ccLicenseBadge' => class Smarty_Variable { ... }, 'section' => class Smarty_Variable { ... }, 'categories' => class Smarty_Variable { ... }, 'primaryGalleys' => class Smarty_Variable { ... }, 'supplementaryGalleys' => class Smarty_Variable { ... }, 'userGroupsById' => class Smarty_Variable { ... }, 'parsedCitations' => class Smarty_Variable { ... }, 'licenseTerms' => class Smarty_Variable { ... }, 'licenseUrl' => class Smarty_Variable { ... }, 'copyrightHolder' => class Smarty_Variable { ... }, 'copyrightYear' => class Smarty_Variable { ... }, 'pubIdPlugins' => class Smarty_Variable { ... }, 'keywords' => class Smarty_Variable { ... }, 'hasAccess' => class Smarty_Variable { ... }, 'citation' => class Smarty_Variable { ... }, 'citationArgs' => class Smarty_Variable { ... }, 'citationArgsJson' => class Smarty_Variable { ... }, 'citationStyles' => class Smarty_Variable { ... }, 'citationDownloads' => class Smarty_Variable { ... }, 'state' => class Smarty_Variable { ... }, 'heading' => class Smarty_Variable { ... }, 'author' => class Smarty_Variable { ... }, 'authorUserGroup' => class Smarty_Variable { ... }, 'doiObject' => class Smarty_Variable { ... }, 'doiUrl' => class Smarty_Variable { ... }, 'translatedDOI' => class Smarty_Variable { ... }, 'translatedKeywords' => class Smarty_Variable { ... }, 'keyword' => class Smarty_Variable { ... }, '__smarty_foreach_keywords' => class Smarty_Variable { ... }, 'hasBiographies' => class Smarty_Variable { ... }, 'authorName' => class Smarty_Variable { ... }, 'authorAffiliation' => class Smarty_Variable { ... }, 'pubIdPlugin' => class Smarty_Variable { ... }, 'pubId' => class Smarty_Variable { ... }, 'addThisProfileId' => class Smarty_Variable { ... }, 'addThisUsername' => class Smarty_Variable { ... }, 'addThisPassword' => class Smarty_Variable { ... }, 'addThisDisplayStyle' => class Smarty_Variable { ... }]; public $parent = class Smarty_Internal_Template { public $_objType = 2; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = [...]; public $parent = class APP\template\TemplateManager { ... }; public $config_vars = [...]; public $ext = class Smarty_Internal_Extension_Handler { ... }; public $cache_id = NULL; public $compile_id = '42362804174f266c598cdb32c3208fc745b92101'; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = [...]; public $_cache = [...]; public $smarty = class APP\template\TemplateManager { ... }; public $source = class Smarty_Template_Source { ... }; public $inheritance = NULL; public $template_resource = 'frontend/pages/article.tpl'; public $mustCompile = FALSE; public $templateId = '/var/www/html/templates/#/var/www/html/plugins/themes/default/templates/#app:frontend/pages/article.tpl##42362804174f266c598cdb32c3208fc745b92101#0'; public $scope = 0; public $isRenderingCache = FALSE; public $startRenderCallbacks = [...]; public $endRenderCallbacks = [...]; public $compiled = class Smarty_Template_Compiled { ... } }; public $config_vars = []; public $ext = class Smarty_Internal_Extension_Handler { public $objType = 2; private $_property_info = [...]; private $resolvedProperties = [...]; public $getTemplateVars = class Smarty_Internal_Method_GetTemplateVars { ... } }; public $cache_id = NULL; public $compile_id = '42362804174f266c598cdb32c3208fc745b92101'; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = []; public $_cache = []; public $smarty = class APP\template\TemplateManager { public $_objType = 1; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = [...]; public $parent = NULL; public $config_vars = [...]; public $ext = class Smarty_Internal_Extension_Handler { ... }; public $cache_id = NULL; public $compile_id = NULL; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = [...]; public $_cache = [...]; public $auto_literal = TRUE; public $error_unassigned = FALSE; public $use_include_path = FALSE; public $_templateDirNormalized = TRUE; public $_joined_template_dir = '/var/www/html/templates/#/var/www/html/plugins/themes/default/templates/'; public $_configDirNormalized = FALSE; public $_joined_config_dir = NULL; public $default_template_handler_func = NULL; public $default_config_handler_func = NULL; public $default_plugin_handler_func = NULL; public $_compileDirNormalized = TRUE; public $_pluginsDirNormalized = FALSE; public $_cacheDirNormalized = FALSE; public $force_compile = FALSE; public $use_sub_dirs = FALSE; public $allow_ambiguous_resources = FALSE; public $merge_compiled_includes = FALSE; public $extends_recursion = TRUE; public $force_cache = FALSE; public $left_delimiter = '{'; public $right_delimiter = '}'; public $literals = [...]; public $security_class = 'Smarty_Security'; public $security_policy = NULL; public $allow_php_templates = FALSE; public $debugging = FALSE; public $debugging_ctrl = 'NONE'; public $smarty_debug_id = 'SMARTY_DEBUG'; public $debug_tpl = NULL; public $error_reporting = 32757; public $config_overwrite = TRUE; public $config_booleanize = TRUE; public $config_read_hidden = FALSE; public $compile_locking = TRUE; public $cache_locking = FALSE; public $locking_timeout = 10; public $default_resource_type = 'app'; public $caching_type = 'file'; public $default_config_type = 'file'; public $cache_modified_check = FALSE; public $registered_plugins = [...]; public $registered_objects = [...]; public $registered_classes = [...]; public $registered_filters = [...]; public $registered_resources = [...]; public $registered_cache_resources = [...]; public $autoload_filters = [...]; public $default_modifiers = [...]; public $escape_html = FALSE; public $start_time = 1732555447.2556; public $_current_file = NULL; public $_parserdebug = FALSE; public $_debug = NULL; protected $template_dir = [...]; protected $_processedTemplateDir = [...]; protected $config_dir = '/var/www/html/cache/t_config'; protected $_processedConfigDir = [...]; protected $compile_dir = '/var/www/html/cache/t_compile/'; protected $plugins_dir = [...]; protected $cache_dir = '/var/www/html/cache/t_cache'; protected $obsoleteProperties = [...]; protected $accessMap = [...]; private ${Smarty}isMutingUndefinedOrNullWarnings = FALSE; private ${PKP\template\PKPTemplateManager}_styleSheets = [...]; private ${PKP\template\PKPTemplateManager}_javaScripts = [...]; private ${PKP\template\PKPTemplateManager}_htmlHeaders = [...]; private ${PKP\template\PKPTemplateManager}_constants = [...]; private ${PKP\template\PKPTemplateManager}_localeKeys = [...]; protected $_state = [...]; private ${PKP\template\PKPTemplateManager}_cacheability = 'no-store'; private ${PKP\template\PKPTemplateManager}_fbv = class PKP\form\FormBuilderVocabulary { ... }; private ${PKP\template\PKPTemplateManager}_request = class APP\core\Request { ... }; private array ${PKP\template\PKPTemplateManager}headers = [...]; private bool ${PKP\template\PKPTemplateManager}isBackendPage = FALSE }; public $source = class Smarty_Template_Source { public $uid = 'addd65021fadf964339ab08cd1aa93ba59b14e9c'; public $resource = 'app:frontend/objects/article_details.tpl'; public $type = 'app'; public $name = 'frontend/objects/article_details.tpl'; public $filepath = 'app:frontendobjectsarticle_details.tpl'; public $timestamp = 1724439197; public $exists = TRUE; public $basename = NULL; public $components = NULL; public $handler = class PKP\template\PKPTemplateResource { ... }; public $smarty = class APP\template\TemplateManager { ... }; public $isConfig = FALSE; public $content = NULL; public $compiler_class = 'Smarty_Internal_SmartyTemplateCompiler'; public $template_lexer_class = 'Smarty_Internal_Templatelexer'; public $template_parser_class = 'Smarty_Internal_Templateparser' }; public $inheritance = NULL; public $template_resource = 'app:frontend/objects/article_details.tpl'; public $mustCompile = FALSE; public $templateId = '36060c7c43ad1691e04870da0cec54c0d1263666'; public $scope = 0; public $isRenderingCache = FALSE; public $startRenderCallbacks = []; public $endRenderCallbacks = []; public $compiled = class Smarty_Template_Compiled { public $filepath = '/var/www/html/cache/t_compile/42362804174f266c598cdb32c3208fc745b92101^addd65021fadf964339ab08cd1aa93ba59b14e9c_0.app.frontendobjectsarticle_details.tpl.php'; public $timestamp = 1732299637; public $exists = TRUE; public $compile_id = NULL; public $processed = TRUE; public $unifunc = 'content_6740cb7578e617_99827455'; public $has_nocache_code = FALSE; public $file_dependency = [...]; public $content = NULL; public $includes = [...]; public $isCache = FALSE; public $nocache_hash = NULL } } ).../smarty_template_resource_base.php:123
200.334725062504PKP\template\PKPTemplateManager->smartyCallHook( $params = ['name' => 'Templates::Article::Details'], $smarty = class Smarty_Internal_Template { public $_objType = 2; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = ['SCRIPT_NAME' => class Smarty_Variable { ... }, 'defaultCharset' => class Smarty_Variable { ... }, 'baseUrl' => class Smarty_Variable { ... }, 'currentContext' => class Smarty_Variable { ... }, 'currentLocale' => class Smarty_Variable { ... }, 'currentLocaleLangDir' => class Smarty_Variable { ... }, 'applicationName' => class Smarty_Variable { ... }, 'dateFormatShort' => class Smarty_Variable { ... }, 'dateFormatLong' => class Smarty_Variable { ... }, 'datetimeFormatShort' => class Smarty_Variable { ... }, 'datetimeFormatLong' => class Smarty_Variable { ... }, 'timeFormat' => class Smarty_Variable { ... }, 'displayPageHeaderTitle' => class Smarty_Variable { ... }, 'displayPageHeaderLogo' => class Smarty_Variable { ... }, 'displayPageHeaderLogoAltText' => class Smarty_Variable { ... }, 'activeTheme' => class Smarty_Variable { ... }, 'requestedPage' => class Smarty_Variable { ... }, 'requestedOp' => class Smarty_Variable { ... }, 'fbvStyles' => class Smarty_Variable { ... }, 'isUserLoggedIn' => class Smarty_Variable { ... }, 'isUserLoggedInAs' => class Smarty_Variable { ... }, 'itemsPerPage' => class Smarty_Variable { ... }, 'numPageLinks' => class Smarty_Variable { ... }, 'siteTitle' => class Smarty_Variable { ... }, 'hasSidebar' => class Smarty_Variable { ... }, 'brandImage' => class Smarty_Variable { ... }, 'sitePublicFilesDir' => class Smarty_Variable { ... }, 'publicFilesDir' => class Smarty_Variable { ... }, 'currentJournal' => class Smarty_Variable { ... }, 'primaryLocale' => class Smarty_Variable { ... }, 'supportedLocales' => class Smarty_Variable { ... }, 'enableAnnouncements' => class Smarty_Variable { ... }, 'disableUserReg' => class Smarty_Variable { ... }, 'pageFooter' => class Smarty_Variable { ... }, 'issue' => class Smarty_Variable { ... }, 'article' => class Smarty_Variable { ... }, 'publication' => class Smarty_Variable { ... }, 'currentPublication' => class Smarty_Variable { ... }, 'galley' => class Smarty_Variable { ... }, 'fileId' => class Smarty_Variable { ... }, 'submissionFileId' => class Smarty_Variable { ... }, 'userRoles' => class Smarty_Variable { ... }, 'firstPublication' => class Smarty_Variable { ... }, 'ccLicenseBadge' => class Smarty_Variable { ... }, 'section' => class Smarty_Variable { ... }, 'categories' => class Smarty_Variable { ... }, 'primaryGalleys' => class Smarty_Variable { ... }, 'supplementaryGalleys' => class Smarty_Variable { ... }, 'userGroupsById' => class Smarty_Variable { ... }, 'parsedCitations' => class Smarty_Variable { ... }, 'licenseTerms' => class Smarty_Variable { ... }, 'licenseUrl' => class Smarty_Variable { ... }, 'copyrightHolder' => class Smarty_Variable { ... }, 'copyrightYear' => class Smarty_Variable { ... }, 'pubIdPlugins' => class Smarty_Variable { ... }, 'keywords' => class Smarty_Variable { ... }, 'hasAccess' => class Smarty_Variable { ... }, 'citation' => class Smarty_Variable { ... }, 'citationArgs' => class Smarty_Variable { ... }, 'citationArgsJson' => class Smarty_Variable { ... }, 'citationStyles' => class Smarty_Variable { ... }, 'citationDownloads' => class Smarty_Variable { ... }, 'state' => class Smarty_Variable { ... }, 'heading' => class Smarty_Variable { ... }, 'author' => class Smarty_Variable { ... }, 'authorUserGroup' => class Smarty_Variable { ... }, 'doiObject' => class Smarty_Variable { ... }, 'doiUrl' => class Smarty_Variable { ... }, 'translatedDOI' => class Smarty_Variable { ... }, 'translatedKeywords' => class Smarty_Variable { ... }, 'keyword' => class Smarty_Variable { ... }, '__smarty_foreach_keywords' => class Smarty_Variable { ... }, 'hasBiographies' => class Smarty_Variable { ... }, 'authorName' => class Smarty_Variable { ... }, 'authorAffiliation' => class Smarty_Variable { ... }, 'pubIdPlugin' => class Smarty_Variable { ... }, 'pubId' => class Smarty_Variable { ... }, 'addThisProfileId' => class Smarty_Variable { ... }, 'addThisUsername' => class Smarty_Variable { ... }, 'addThisPassword' => class Smarty_Variable { ... }, 'addThisDisplayStyle' => class Smarty_Variable { ... }]; public $parent = class Smarty_Internal_Template { public $_objType = 2; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = [...]; public $parent = class APP\template\TemplateManager { ... }; public $config_vars = [...]; public $ext = class Smarty_Internal_Extension_Handler { ... }; public $cache_id = NULL; public $compile_id = '42362804174f266c598cdb32c3208fc745b92101'; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = [...]; public $_cache = [...]; public $smarty = class APP\template\TemplateManager { ... }; public $source = class Smarty_Template_Source { ... }; public $inheritance = NULL; public $template_resource = 'frontend/pages/article.tpl'; public $mustCompile = FALSE; public $templateId = '/var/www/html/templates/#/var/www/html/plugins/themes/default/templates/#app:frontend/pages/article.tpl##42362804174f266c598cdb32c3208fc745b92101#0'; public $scope = 0; public $isRenderingCache = FALSE; public $startRenderCallbacks = [...]; public $endRenderCallbacks = [...]; public $compiled = class Smarty_Template_Compiled { ... } }; public $config_vars = []; public $ext = class Smarty_Internal_Extension_Handler { public $objType = 2; private $_property_info = [...]; private $resolvedProperties = [...]; public $getTemplateVars = class Smarty_Internal_Method_GetTemplateVars { ... } }; public $cache_id = NULL; public $compile_id = '42362804174f266c598cdb32c3208fc745b92101'; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = []; public $_cache = []; public $smarty = class APP\template\TemplateManager { public $_objType = 1; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = [...]; public $parent = NULL; public $config_vars = [...]; public $ext = class Smarty_Internal_Extension_Handler { ... }; public $cache_id = NULL; public $compile_id = NULL; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = [...]; public $_cache = [...]; public $auto_literal = TRUE; public $error_unassigned = FALSE; public $use_include_path = FALSE; public $_templateDirNormalized = TRUE; public $_joined_template_dir = '/var/www/html/templates/#/var/www/html/plugins/themes/default/templates/'; public $_configDirNormalized = FALSE; public $_joined_config_dir = NULL; public $default_template_handler_func = NULL; public $default_config_handler_func = NULL; public $default_plugin_handler_func = NULL; public $_compileDirNormalized = TRUE; public $_pluginsDirNormalized = FALSE; public $_cacheDirNormalized = FALSE; public $force_compile = FALSE; public $use_sub_dirs = FALSE; public $allow_ambiguous_resources = FALSE; public $merge_compiled_includes = FALSE; public $extends_recursion = TRUE; public $force_cache = FALSE; public $left_delimiter = '{'; public $right_delimiter = '}'; public $literals = [...]; public $security_class = 'Smarty_Security'; public $security_policy = NULL; public $allow_php_templates = FALSE; public $debugging = FALSE; public $debugging_ctrl = 'NONE'; public $smarty_debug_id = 'SMARTY_DEBUG'; public $debug_tpl = NULL; public $error_reporting = 32757; public $config_overwrite = TRUE; public $config_booleanize = TRUE; public $config_read_hidden = FALSE; public $compile_locking = TRUE; public $cache_locking = FALSE; public $locking_timeout = 10; public $default_resource_type = 'app'; public $caching_type = 'file'; public $default_config_type = 'file'; public $cache_modified_check = FALSE; public $registered_plugins = [...]; public $registered_objects = [...]; public $registered_classes = [...]; public $registered_filters = [...]; public $registered_resources = [...]; public $registered_cache_resources = [...]; public $autoload_filters = [...]; public $default_modifiers = [...]; public $escape_html = FALSE; public $start_time = 1732555447.2556; public $_current_file = NULL; public $_parserdebug = FALSE; public $_debug = NULL; protected $template_dir = [...]; protected $_processedTemplateDir = [...]; protected $config_dir = '/var/www/html/cache/t_config'; protected $_processedConfigDir = [...]; protected $compile_dir = '/var/www/html/cache/t_compile/'; protected $plugins_dir = [...]; protected $cache_dir = '/var/www/html/cache/t_cache'; protected $obsoleteProperties = [...]; protected $accessMap = [...]; private ${Smarty}isMutingUndefinedOrNullWarnings = FALSE; private ${PKP\template\PKPTemplateManager}_styleSheets = [...]; private ${PKP\template\PKPTemplateManager}_javaScripts = [...]; private ${PKP\template\PKPTemplateManager}_htmlHeaders = [...]; private ${PKP\template\PKPTemplateManager}_constants = [...]; private ${PKP\template\PKPTemplateManager}_localeKeys = [...]; protected $_state = [...]; private ${PKP\template\PKPTemplateManager}_cacheability = 'no-store'; private ${PKP\template\PKPTemplateManager}_fbv = class PKP\form\FormBuilderVocabulary { ... }; private ${PKP\template\PKPTemplateManager}_request = class APP\core\Request { ... }; private array ${PKP\template\PKPTemplateManager}headers = [...]; private bool ${PKP\template\PKPTemplateManager}isBackendPage = FALSE }; public $source = class Smarty_Template_Source { public $uid = 'addd65021fadf964339ab08cd1aa93ba59b14e9c'; public $resource = 'app:frontend/objects/article_details.tpl'; public $type = 'app'; public $name = 'frontend/objects/article_details.tpl'; public $filepath = 'app:frontendobjectsarticle_details.tpl'; public $timestamp = 1724439197; public $exists = TRUE; public $basename = NULL; public $components = NULL; public $handler = class PKP\template\PKPTemplateResource { ... }; public $smarty = class APP\template\TemplateManager { ... }; public $isConfig = FALSE; public $content = NULL; public $compiler_class = 'Smarty_Internal_SmartyTemplateCompiler'; public $template_lexer_class = 'Smarty_Internal_Templatelexer'; public $template_parser_class = 'Smarty_Internal_Templateparser' }; public $inheritance = NULL; public $template_resource = 'app:frontend/objects/article_details.tpl'; public $mustCompile = FALSE; public $templateId = '36060c7c43ad1691e04870da0cec54c0d1263666'; public $scope = 0; public $isRenderingCache = FALSE; public $startRenderCallbacks = []; public $endRenderCallbacks = []; public $compiled = class Smarty_Template_Compiled { public $filepath = '/var/www/html/cache/t_compile/42362804174f266c598cdb32c3208fc745b92101^addd65021fadf964339ab08cd1aa93ba59b14e9c_0.app.frontendobjectsarticle_details.tpl.php'; public $timestamp = 1732299637; public $exists = TRUE; public $compile_id = NULL; public $processed = TRUE; public $unifunc = 'content_6740cb7578e617_99827455'; public $has_nocache_code = FALSE; public $file_dependency = [...]; public $content = NULL; public $includes = [...]; public $isCache = FALSE; public $nocache_hash = NULL } } ).../42362804174f266c598cdb32c3208fc745b92101^addd65021fadf964339ab08cd1aa93ba59b14e9c_0.app.frontendobjectsarticle_details.tpl.php:560
210.334725062944PKP\plugins\Hook::call( $hookName = 'Templates::Article::Details', $args = [0 => ['name' => 'Templates::Article::Details'], 1 => class Smarty_Internal_Template { public $_objType = 2; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = [...]; public $parent = class Smarty_Internal_Template { ... }; public $config_vars = [...]; public $ext = class Smarty_Internal_Extension_Handler { ... }; public $cache_id = NULL; public $compile_id = '42362804174f266c598cdb32c3208fc745b92101'; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = [...]; public $_cache = [...]; public $smarty = class APP\template\TemplateManager { ... }; public $source = class Smarty_Template_Source { ... }; public $inheritance = NULL; public $template_resource = 'app:frontend/objects/article_details.tpl'; public $mustCompile = FALSE; public $templateId = '36060c7c43ad1691e04870da0cec54c0d1263666'; public $scope = 0; public $isRenderingCache = FALSE; public $startRenderCallbacks = [...]; public $endRenderCallbacks = [...]; public $compiled = class Smarty_Template_Compiled { ... } }, 2 => '\t<div class="item citation">\n\t\t<section class="sub_item citation_display">\n\t\t\t<h2 class="label">\n\t\t\t\tHow to Cite\n\t\t\t</h2>\n\t\t\t<div class="value">\n\t\t\t\t<div id="citationOutput" role="region" aria-live="polite">\n\t\t\t\t\t<div class="csl-bib-body">\n <div class="csl-entry"><div class="csl-left-margin">1.</div><div class="csl-right-inline">Development of Rapid and Low Cost Analytical Methods for the Quality Control of Antidiabetic Medications Used in Brazil in the Unified Health System. Com. Ciências Saúde [Interne'...] ).../PKPTemplateManager.php:1784
220.334725063320PKP\plugins\Hook::run( $hookName = 'Templates::Article::Details', $args = [0 => [0 => [...], 1 => class Smarty_Internal_Template { ... }, 2 => '\t<div class="item citation">\n\t\t<section class="sub_item citation_display">\n\t\t\t<h2 class="label">\n\t\t\t\tHow to Cite\n\t\t\t</h2>\n\t\t\t<div class="value">\n\t\t\t\t<div id="citationOutput" role="region" aria-live="polite">\n\t\t\t\t\t<div class="csl-bib-body">\n <div class="csl-entry"><div class="csl-left-margin">1.</div><div class="csl-right-inline">Development of Rapid and Low Cost Analytical Methods for the Quality Control of Antidiabetic Medications Used in Brazil in the Unified Health System. Com. Ciências Saúde [Interne'...]] ).../Hook.php:113
230.335425112440call_user_func_array:{/var/www/html/lib/pkp/classes/plugins/Hook.php:139}( $callback = [0 => class APP\plugins\generic\citations\CitationsPlugin { public $pluginPath = 'plugins/generic/citations'; public $pluginCategory = 'generic'; public $request = NULL }, 1 => 'citationsContent'], $args = [0 => 'Templates::Article::Details', 1 => [0 => [...], 1 => class Smarty_Internal_Template { ... }, 2 => '\t<div class="item citation">\n\t\t<section class="sub_item citation_display">\n\t\t\t<h2 class="label">\n\t\t\t\tHow to Cite\n\t\t\t</h2>\n\t\t\t<div class="value">\n\t\t\t\t<div id="citationOutput" role="region" aria-live="polite">\n\t\t\t\t\t<div class="csl-bib-body">\n <div class="csl-entry"><div class="csl-left-margin">1.</div><div class="csl-right-inline">Development of Rapid and Low Cost Analytical Methods for the Quality Control of Antidiabetic Medications Used in Brazil in the Unified Health System. Com. Ciências Saúde [Interne'...]] ).../Hook.php:139
240.335425112768APP\plugins\generic\citations\CitationsPlugin->citationsContent( $hookName = 'Templates::Article::Details', $args = [0 => ['name' => 'Templates::Article::Details'], 1 => class Smarty_Internal_Template { public $_objType = 2; public $template_class = 'Smarty_Internal_Template'; public $tpl_vars = [...]; public $parent = class Smarty_Internal_Template { ... }; public $config_vars = [...]; public $ext = class Smarty_Internal_Extension_Handler { ... }; public $cache_id = NULL; public $compile_id = '42362804174f266c598cdb32c3208fc745b92101'; public $caching = 0; public $compile_check = 1; public $cache_lifetime = 3600; public $tplFunctions = [...]; public $_cache = [...]; public $smarty = class APP\template\TemplateManager { ... }; public $source = class Smarty_Template_Source { ... }; public $inheritance = NULL; public $template_resource = 'app:frontend/objects/article_details.tpl'; public $mustCompile = FALSE; public $templateId = '36060c7c43ad1691e04870da0cec54c0d1263666'; public $scope = 0; public $isRenderingCache = FALSE; public $startRenderCallbacks = [...]; public $endRenderCallbacks = [...]; public $compiled = class Smarty_Template_Compiled { ... } }, 2 => '\t<div class="item citation">\n\t\t<section class="sub_item citation_display">\n\t\t\t<h2 class="label">\n\t\t\t\tHow to Cite\n\t\t\t</h2>\n\t\t\t<div class="value">\n\t\t\t\t<div id="citationOutput" role="region" aria-live="polite">\n\t\t\t\t\t<div class="csl-bib-body">\n <div class="csl-entry"><div class="csl-left-margin">1.</div><div class="csl-right-inline">Development of Rapid and Low Cost Analytical Methods for the Quality Control of Antidiabetic Medications Used in Brazil in the Unified Health System. Com. Ciências Saúde [Interne'...] ).../Hook.php:139
250.335525113608json_decode( $json = NULL, $associative = TRUE ).../CitationsPlugin.php:68

How to Cite

1.
Development of Rapid and Low Cost Analytical Methods for the Quality Control of Antidiabetic Medications Used in Brazil in the Unified Health System. Com. Ciências Saúde [Internet]. 2018 Feb. 2 [cited 2024 Nov. 25];28(01):45-8. Available from: https://revistaccs.espdf.fepecs.edu.br/index.php/comunicacaoemcienciasdasaude/article/view/114

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